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用霍乱毒素/类毒素免疫大鼠以预防大肠杆菌不耐热肠毒素攻击。

Protection against challenge with Escherichia coli heat-labile enterotoxin by immunization of rats with cholera toxin/toxoid.

作者信息

Pierce N F

出版信息

Infect Immun. 1977 Nov;18(2):338-41. doi: 10.1128/iai.18.2.338-341.1977.

Abstract

Rats were used to study dose-response curves to intestinal challenge with cholera toxin or Escherichia coli heat-labile enterotoxin. Prior immunization with cholera toxin/toxoid induced significant and equal protection against both toxins.

摘要

用大鼠研究霍乱毒素或大肠杆菌不耐热肠毒素肠道攻击的剂量反应曲线。预先用霍乱毒素/类毒素免疫可诱导对两种毒素产生显著且相等的保护作用。

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本文引用的文献

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Cutaneous responses to cholera skin toxin in man. I. Responses in unimmunized American males.
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Infect Immun. 1973 Oct;8(4):641-4. doi: 10.1128/iai.8.4.641-644.1973.
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Cellular kinetics of the intestinal immune response to cholera toxoid in rats.
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