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1
Protection against challenge with Escherichia coli heat-labile enterotoxin by immunization of rats with cholera toxin/toxoid.用霍乱毒素/类毒素免疫大鼠以预防大肠杆菌不耐热肠毒素攻击。
Infect Immun. 1977 Nov;18(2):338-41. doi: 10.1128/iai.18.2.338-341.1977.
2
The sigma ligand, igmesine, inhibits cholera toxin and Escherichia coli enterotoxin induced jejunal secretion in the rat.西格玛配体伊格美辛可抑制霍乱毒素和大肠杆菌肠毒素诱导的大鼠空肠分泌。
Gut. 1999 Oct;45(4):564-9. doi: 10.1136/gut.45.4.564.
3
Differences in cross-protection in rats immunized with the B subunits of cholera toxin and Escherichia coli heat-labile toxin.用霍乱毒素B亚单位和大肠杆菌不耐热毒素免疫的大鼠交叉保护作用的差异。
Infect Immun. 1984 Mar;43(3):811-6. doi: 10.1128/iai.43.3.811-816.1984.
4
Inhibition of heat-labile cholera and Escherichia coli enterotoxins by brefeldin A.布雷菲德菌素A对热不稳定霍乱毒素和大肠杆菌肠毒素的抑制作用。
Infect Immun. 1993 Aug;61(8):3282-6. doi: 10.1128/iai.61.8.3282-3286.1993.
5
Experimental studies on cholera immunization. II. Evidence for protective antitoxic immunity mediated by serum antibodies as well as local antibodies.霍乱免疫的实验研究。II. 血清抗体和局部抗体介导保护性抗毒素免疫的证据。
Infect Immun. 1972 May;5(5):662-7. doi: 10.1128/iai.5.5.662-667.1972.
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Evaluation of BW942C, a novel antidiarrheal agent, against enterotoxins of Escherichia coli and Vibrio cholerae.新型止泻剂BW942C对大肠杆菌和霍乱弧菌肠毒素的评估。
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Infect Immun. 1983 Jun;40(3):924-9. doi: 10.1128/iai.40.3.924-929.1983.
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Inhibitory effect of indomethacin on skin permeability reactions mediated by heat-labile enterotoxins of Salmonella weltevreden, Escherichia coli and Vibrio cholerae.消炎痛对肠炎沙门氏菌、大肠杆菌和霍乱弧菌不耐热肠毒素介导的皮肤通透性反应的抑制作用。
Zentralbl Bakteriol Mikrobiol Hyg A Med Mikrobiol Infekt Parasitol. 1982 May;252(1):35-42.
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Structural biology and structure-based inhibitor design of cholera toxin and heat-labile enterotoxin.霍乱毒素和不耐热肠毒素的结构生物学及基于结构的抑制剂设计
Int J Med Microbiol. 2004 Oct;294(4):217-23. doi: 10.1016/j.ijmm.2004.07.002.
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Comparison of the tissue receptors for Vibrio cholerae and Escherichia coli enterotoxins by means of gangliosides and natural cholera toxoid.利用神经节苷脂和天然霍乱类毒素比较霍乱弧菌和大肠杆菌肠毒素的组织受体
Infect Immun. 1973 Dec;8(6):851-9. doi: 10.1128/iai.8.6.851-859.1973.

引用本文的文献

1
Suppression of the intestinal immune response to cholera toxin by specific serum antibody.特异性血清抗体对肠道针对霍乱毒素免疫反应的抑制作用。
Infect Immun. 1980 Oct;30(1):62-8. doi: 10.1128/iai.30.1.62-68.1980.
2
Development of a vaccine against experimental cholera and Escherichia coli diarrheal disease.针对实验性霍乱和大肠杆菌腹泻病的疫苗研发。
Infect Immun. 1981 May;32(2):534-41. doi: 10.1128/iai.32.2.534-541.1981.
3
Enterotoxigenic Escherichia coli diarrhoea: acquired immunity and transmission in an endemic area.产肠毒素大肠杆菌腹泻：流行地区的获得性免疫与传播
Bull World Health Organ. 1981;59(2):263-8.
4
Protective effect of immunization of rats with holotoxin or B subunit of Escherichia coli heat-labile enterotoxin.用大肠杆菌不耐热肠毒素全毒素或B亚基免疫大鼠的保护作用。
Infect Immun. 1981 Jan;31(1):144-50. doi: 10.1128/iai.31.1.144-150.1981.
5
Influence of route of administration on immediate and extended protection in rats immunized with Escherichia coli heart-labile enterotoxin.给药途径对用大肠杆菌不耐热肠毒素免疫的大鼠的即刻和持久保护作用的影响。
Infect Immun. 1980 Jan;27(1):81-6. doi: 10.1128/iai.27.1.81-86.1980.
6
Differences in cross-protection in rats immunized with the B subunits of cholera toxin and Escherichia coli heat-labile toxin.用霍乱毒素B亚单位和大肠杆菌不耐热毒素免疫的大鼠交叉保护作用的差异。
Infect Immun. 1984 Mar;43(3):811-6. doi: 10.1128/iai.43.3.811-816.1984.
7
IgA antibodies in rat bile inhibit cholera toxin-induced secretion in ileal loops in situ.大鼠胆汁中的IgA抗体可抑制霍乱毒素诱导的原位回肠袢分泌。
Immunology. 1985 Aug;55(4):579-83.
8
Enterotoxigenic Escherichia coli diarrhea in an endemic area prepares the intestine for an anamnestic immunoglobulin A antitoxin response to oral cholera B subunit vaccination.在地方性流行地区，产肠毒素大肠杆菌腹泻可使肠道对口服霍乱B亚单位疫苗产生回忆性免疫球蛋白A抗毒素反应做好准备。
Infect Immun. 1988 Jan;56(1):230-3. doi: 10.1128/iai.56.1.230-233.1988.
9
Comparative immunogenicities of Vi polysaccharide-protein conjugates composed of cholera toxin or its B subunit as a carrier bound to high- or lower-molecular-weight Vi.由霍乱毒素或其B亚基作为载体与高分子量或低分子量Vi结合而成的Vi多糖-蛋白质结合物的比较免疫原性
Infect Immun. 1989 Dec;57(12):3823-7. doi: 10.1128/iai.57.12.3823-3827.1989.
10
Protective effect of active immunization with purified Escherichia coli heat-labile enterotoxin in rats.纯化大肠杆菌不耐热肠毒素主动免疫对大鼠的保护作用。
Infect Immun. 1979 Mar;23(3):592-9. doi: 10.1128/iai.23.3.592-599.1979.

本文引用的文献

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Immunochemical Studies of Two Cholera Toxin-Containing Standard Culture Filtrate Preparations of Vibrio cholerae.霍乱弧菌两种含霍乱毒素标准培养滤液制剂的免疫化学研究。
Infect Immun. 1971 Jun;3(6):747-55. doi: 10.1128/iai.3.6.747-755.1971.
2
Antitoxic immunity in experimental cholera: observations with purified antigens and the ligated ileal loop model.实验性霍乱的抗毒免疫：用纯化抗原和结扎回肠袢模型的观察。
Infect Immun. 1970 May;1(5):464-7. doi: 10.1128/iai.1.5.464-467.1970.
3
Antitoxic immunity in experimental canine cholera.实验性犬霍乱中的抗毒免疫
J Infect Dis. 1970 May;121(5):463-70. doi: 10.1093/infdis/121.5.463.
4
Cutaneous responses to cholera skin toxin in man. I. Responses in unimmunized American males.人类对霍乱皮肤毒素的皮肤反应。I. 未免疫的美国男性的反应。
J Infect Dis. 1972 Mar;125(3):203-15. doi: 10.1093/infdis/125.3.203.
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Protection against experimental cholera by antitoxin.抗毒素对实验性霍乱的保护作用。
J Infect Dis. 1972 Dec;126(6):606-16. doi: 10.1093/infdis/126.6.606.
6
Immunization with Escherichia coli enterotoxin protects against homologous enterotoxin challenge.用大肠杆菌肠毒素进行免疫可抵御同源肠毒素攻击。
Infect Immun. 1973 Oct;8(4):641-4. doi: 10.1128/iai.8.4.641-644.1973.
7
Immunologic cross-reactions of enterotoxins from Escherichia coli and Vibrio cholerae.大肠杆菌和霍乱弧菌肠毒素的免疫交叉反应
J Infect Dis. 1973 Feb;127(2):164-70. doi: 10.1093/infdis/127.2.164.
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Cellular kinetics of the intestinal immune response to cholera toxoid in rats.大鼠对霍乱类毒素肠道免疫反应的细胞动力学
J Exp Med. 1975 Dec 1;142(6):1550-63. doi: 10.1084/jem.142.6.1550.
9
Immunity to experimental cholera. III. Enhanced duration of protection after sequential parenteral-oral administration of toxoid to dogs.实验性霍乱免疫。III. 对犬类先后进行肠胃外-口服类毒素给药后保护期的延长
J Infect Dis. 1977 Jun;135(6):888-96. doi: 10.1093/infdis/135.6.888.
10
Challenge of dogs with live enterotoxigenic Escherichia coli and effects of repeated challenges on fluid secretion in jejunal Thiry-Vella loops.
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用霍乱毒素/类毒素免疫大鼠以预防大肠杆菌不耐热肠毒素攻击。

Protection against challenge with Escherichia coli heat-labile enterotoxin by immunization of rats with cholera toxin/toxoid.

作者信息

Pierce N F

出版信息

Infect Immun. 1977 Nov;18(2):338-41. doi: 10.1128/iai.18.2.338-341.1977.

DOI:10.1128/iai.18.2.338-341.1977
PMID:336542
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC421236/
Abstract

Rats were used to study dose-response curves to intestinal challenge with cholera toxin or Escherichia coli heat-labile enterotoxin. Prior immunization with cholera toxin/toxoid induced significant and equal protection against both toxins.

摘要

用大鼠研究霍乱毒素或大肠杆菌不耐热肠毒素肠道攻击的剂量反应曲线。预先用霍乱毒素/类毒素免疫可诱导对两种毒素产生显著且相等的保护作用。