用霍乱毒素/类毒素免疫大鼠以预防大肠杆菌不耐热肠毒素攻击。
Protection against challenge with Escherichia coli heat-labile enterotoxin by immunization of rats with cholera toxin/toxoid.
作者信息
Pierce N F
出版信息
Infect Immun. 1977 Nov;18(2):338-41. doi: 10.1128/iai.18.2.338-341.1977.
Abstract
Rats were used to study dose-response curves to intestinal challenge with cholera toxin or Escherichia coli heat-labile enterotoxin. Prior immunization with cholera toxin/toxoid induced significant and equal protection against both toxins.
摘要
用大鼠研究霍乱毒素或大肠杆菌不耐热肠毒素肠道攻击的剂量反应曲线。预先用霍乱毒素/类毒素免疫可诱导对两种毒素产生显著且相等的保护作用。
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本文引用的文献
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Immunochemical Studies of Two Cholera Toxin-Containing Standard Culture Filtrate Preparations of Vibrio cholerae.霍乱弧菌两种含霍乱毒素标准培养滤液制剂的免疫化学研究。
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Antitoxic immunity in experimental cholera: observations with purified antigens and the ligated ileal loop model.实验性霍乱的抗毒免疫：用纯化抗原和结扎回肠袢模型的观察。
Infect Immun. 1970 May;1(5):464-7. doi: 10.1128/iai.1.5.464-467.1970.
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Antitoxic immunity in experimental canine cholera.实验性犬霍乱中的抗毒免疫
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Protection against experimental cholera by antitoxin.抗毒素对实验性霍乱的保护作用。
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Challenge of dogs with live enterotoxigenic Escherichia coli and effects of repeated challenges on fluid secretion in jejunal Thiry-Vella loops.
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