Newton B W, Hamill R W
Neurology Unit, Monroe Community Hospital, Rochester, NY 14603.
Brain Res Bull. 1988 Mar;20(3):349-60. doi: 10.1016/0361-9230(88)90064-0.
An immunohistochemically derived morphological description of a diverse population of rat lamina VII and X intraspinal 5HT neurons is provided. These bipolar or multipolar neurons occur most frequently in lamina X, dorsal or dorsolateral to the central canal, in thoracolumbar, sacral, and coccygeal spinal segments. These 5HT intraspinal neurons are found in normal rat spinal cords as well as in spinal cords that have been hemisected or transected 60 days prior to serotonin immunostaining. Therefore, 5HT intraspinal neurons are the probable source of the biochemically detectable 5HT that remains in the spinal cord distal to a spinal transection. In the rat, serotonin intraspinal neurons are most often associated with spinal autonomic nuclei but it is unknown if they are preganglionic in nature.
本文提供了对大鼠脊髓板层VII和X中多种5-羟色胺（5HT）脊髓内神经元群体的免疫组织化学形态学描述。这些双极或多极神经元最常出现在脊髓板层X中，位于中央管背侧或背外侧，在胸腰段、骶段和尾段脊髓节段。这些5HT脊髓内神经元在正常大鼠脊髓以及在5-羟色胺免疫染色前60天已进行半切或横切的脊髓中均有发现。因此，5HT脊髓内神经元可能是脊髓横断后在脊髓远端仍可生化检测到的5HT的来源。在大鼠中，5HT脊髓内神经元最常与脊髓自主神经核相关，但它们在本质上是否为节前神经元尚不清楚。
