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大鼠脊髓自主神经区域中5-羟色胺神经元的免疫组织化学显示

Immunohistochemical demonstration of serotonin neurons in autonomic regions of the rat spinal cord.

作者信息

Newton B W, Maley B E, Hamill R W

出版信息

Brain Res. 1986 Jun 18;376(1):155-63. doi: 10.1016/0006-8993(86)90910-8.

DOI:10.1016/0006-8993(86)90910-8
PMID:3719364
Abstract

The immunohistochemical distribution of serotonin neurons in normal and transected spinal cords of rats was examined. Intraspinal serotonin neurons were immunostained as far rostral and caudal as T3 and Co1, respectively. All serotonin neurons were located in lamina VII and X, and most were located in spinal autonomic areas. Both bipolar and multipolar neurons were observed with many of the neurons oriented longitudinally to the long axis of the cord. Spinal neurons immunostained for serotonin were visible with and without L-tryptophan and monoamine oxidase inhibitor pretreatment.

摘要

研究了正常和横断大鼠脊髓中5-羟色胺神经元的免疫组织化学分布。脊髓内的5-羟色胺神经元分别在T3和Co1水平的头侧和尾侧被免疫染色。所有5-羟色胺神经元均位于VII层和X层,且大多数位于脊髓自主神经区域。观察到双极和多极神经元,其中许多神经元沿脊髓长轴纵向排列。无论有无L-色氨酸和单胺氧化酶抑制剂预处理,均可观察到脊髓中5-羟色胺免疫染色的神经元。

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