紫外线辐射对皮肤光老化的影响——体外研究综述。
The impact of ultraviolet radiation on skin photoaging - review of in vitro studies.
机构信息
Department of Bromatology, Medical University of Białystok, Białystok, Poland.
出版信息
J Cosmet Dermatol. 2021 Nov;20(11):3427-3431. doi: 10.1111/jocd.14033. Epub 2021 Mar 13.
Abstract
BACKGROUND
Photoaging, ultra violet (UV) induced skin aging is a gradual process that depends on the time and intensity of solar radiation.
AIM
The aim of this paper was to review of the literature focused on in vitro studies explaining the mechanisms of photoaging.
METHODS
Electronic databases, including PubMed and MEDLINE, were searched for in vitro studies on the importance of UV radiation in the skin photoaging process of peer-reviewed scientific journals. Only articles available in English and full version publications were considered for this review.
RESULTS
Three main modes of UV radiation action on skin cells which lead to photoaging, there are changes in cell metabolism, induction of oxidative stress due to the change in enzyme activity.
CONCLUSION
The information gathered in this publication will help to better understand the complex and multidirectional mechanism of skin photoaging, which will contribute to the development of research on potential cosmetic products that provide effective and safe sun protection or repair damage caused by UV radiation.
摘要
背景
光老化，即紫外线（UV）诱导的皮肤老化是一个渐进的过程，取决于太阳辐射的时间和强度。
目的
本文旨在回顾文献，重点关注解释光老化机制的体外研究。
方法
检索了包括 PubMed 和 MEDLINE 在内的电子数据库，以查找有关同行评议科学期刊中紫外线辐射在皮肤光老化过程中重要性的体外研究。仅考虑了可获得英文全文的文章。
结果
紫外线辐射对皮肤细胞有三种主要作用模式，这些作用模式导致光老化，包括改变细胞代谢、由于酶活性的改变诱导氧化应激。
结论
本出版物中收集的信息将有助于更好地理解皮肤光老化的复杂和多向机制，这将有助于开发提供有效和安全的防晒或修复紫外线辐射造成的损伤的潜在美容产品的研究。
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