Department of Bioinformatics and Biotechnology, Government College University Allama Iqbal Road, 38000 Faisalabad, Pakistan.
Department of Zoology, Government College University Allama Iqbal Road, 38000 Faisalabad, Pakistan.
Curr Pharm Des. 2021;27(20):2344-2365. doi: 10.2174/1381612827666210303141416.
A silent monster, breast cancer, is a challenging medical task for researchers. Breast cancer is a leading cause of death in women with respect to other cancers. A case of breast cancer is diagnosed among women every 19 seconds, and every 74 seconds, a woman dies of breast cancer somewhere in the world. Several risk factors, such as genetic and environmental factors, favor breast cancer development. This review tends to provide deep insights regarding the genetics of breast cancer along with multiple diagnostic and therapeutic approaches as problem-solving negotiators to prevent the progression of breast cancer. This assembled data mainly aims to discuss omics-based approaches to provide enthralling diagnostic biomarkers and emerging novel therapies to combat breast cancer. This review article intends to pave a new path for the discovery of effective treatment options.
一种沉默的杀手——乳腺癌,是研究人员面临的一项艰巨的医学任务。乳腺癌是女性因癌症而死亡的主要原因。每 19 秒就有一名女性被诊断出患有乳腺癌,每 74 秒,全球就有一名女性死于乳腺癌。一些风险因素,如遗传和环境因素,有利于乳腺癌的发展。本篇综述旨在提供关于乳腺癌遗传学的深入见解,以及多种诊断和治疗方法,以作为解决问题的谈判者来预防乳腺癌的进展。这些综合数据主要旨在讨论基于组学的方法,以提供引人入胜的诊断生物标志物和新兴的新型疗法来对抗乳腺癌。本文旨在为发现有效的治疗选择开辟新途径。