巴西亚马逊地区一家三级医疗机构中被矛头蝮蛇咬伤患者的严重组织并发症：临床特征和相关因素。
Severe tissue complications in patients of Bothrops snakebite at a tertiary health unit in the Brazilian Amazon: clinical characteristics and associated factors.
机构信息
Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Instituto de Pesquisa Clínica Carlos Borborema, Manaus, AM, Brasil.
Universidade do Estado do Amazonas, Programa de Pós-Graduação em Medicina Tropical, Manaus, AM, Brasil.
出版信息
Rev Soc Bras Med Trop. 2021 Feb 26;54:e03742020. doi: 10.1590/0037-8682-0374-2020.
Abstract
INTRODUCTION
Snakebites in the Brazilian Amazon are caused mostly by snakes from the Bothrops genus and envenomated patients may suffer from tissue complications.
METHODS
This study aimed to identify risk factors for severe tissue complications (STC) in patients with Bothrops snakebite in the Amazonas state, Brazil.
RESULTS
Snakebites that were classified as severe and affected female patients with comorbidities presented greater risks of developing STCs. In addition, hospitalizations of patients with STC exceeded 5 days.
CONCLUSIONS
Clinical and epidemiological characteristics can prove essential for assessing the evolution of STC and clinical prognosis of patients with Bothrops snakebites.
摘要
简介
在巴西亚马逊地区，蛇伤主要由矛头蝮属的蛇引起，被蛇咬伤的患者可能会出现组织并发症。
方法
本研究旨在确定巴西亚马逊州被矛头蝮属蛇咬伤患者发生严重组织并发症（STC）的危险因素。
结果
被归类为严重的蛇伤和患有合并症的女性患者发生 STC 的风险更高。此外，发生 STC 的患者的住院时间超过 5 天。
结论
临床和流行病学特征对于评估 STC 的演变和矛头蝮属蛇咬伤患者的临床预后至关重要。
相似文献
1
Severe tissue complications in patients of Bothrops snakebite at a tertiary health unit in the Brazilian Amazon: clinical characteristics and associated factors.巴西亚马逊地区一家三级医疗机构中被矛头蝮蛇咬伤患者的严重组织并发症：临床特征和相关因素。
Rev Soc Bras Med Trop. 2021 Feb 26;54:e03742020. doi: 10.1590/0037-8682-0374-2020.
2
Acute kidney injury caused by bothrops snake venom.由矛头蝮蛇毒液引起的急性肾损伤。
Nephron Clin Pract. 2011;119(2):c131-6; discussion c137. doi: 10.1159/000324228. Epub 2011 Jul 8.
3
Relationship between snake size and clinical, epidemiological and laboratory aspects of Bothrops atrox snakebites in the Western Brazilian Amazon.巴西西部亚马逊地区响尾蛇咬伤的蛇体大小与临床、流行病学和实验室方面的关系。
Toxicon. 2020 Oct 30;186:160-167. doi: 10.1016/j.toxicon.2020.08.010. Epub 2020 Aug 19.
4
Snakebites caused by the genera Bothrops and Lachesis in the Brazilian Amazon: a study of factors associated with severe cases and death.巴西亚马逊地区的 Bothrops 和 Lachesis 属蛇咬伤：严重病例和死亡相关因素的研究。
Rev Soc Bras Med Trop. 2022 Jul 25;55:e05582021. doi: 10.1590/0037-8682-0558-2021. eCollection 2022.
5
Use of freeze-dried trivalent antivenom to neutralize the toxic activities of Bothrops atrox snake venoms from the Amazon.使用冻干的三种蛇毒抗毒素来中和亚马逊流域矛头蝮蛇毒的毒性。
Toxicon. 2021 Sep;200:19-22. doi: 10.1016/j.toxicon.2021.06.015. Epub 2021 Jun 29.
6
Ethno-knowledge and attitudes regarding snakebites in the Alto Juruá region, Western Brazilian Amazonia.巴西亚马逊西部地区 Alto Juruá 地区的民族蛇伤知识和态度。
Toxicon. 2019 Dec 5;171:66-77. doi: 10.1016/j.toxicon.2019.10.238. Epub 2019 Oct 16.
7
Fatal stroke after Bothrops snakebite in the Amazonas state, Brazil: A case report.巴西亚马孙州发生的因被矛头蝮蛇咬伤导致的致命中风：病例报告。
Toxicon. 2017 Nov;138:102-106. doi: 10.1016/j.toxicon.2017.08.021. Epub 2017 Aug 24.
8
[Envenomation by Bothrops in the State of Bahia: epidemiological and clinical aspects].[巴伊亚州的具窍蝮蛇咬伤：流行病学和临床方面]
Rev Soc Bras Med Trop. 2007 Sep-Oct;40(5):569-73. doi: 10.1590/s0037-86822007000500015.
9
Long-term disability after cerebral ischemic stroke following a Bothrops atrox snakebite in the Brazilian Amazon.巴西亚马逊地区被矛头蝮蛇咬伤后导致脑缺血性脑卒中引起的长期残疾。
Toxicon. 2024 Aug 28;247:107793. doi: 10.1016/j.toxicon.2024.107793. Epub 2024 Jun 3.
10
"": predicting venom-induced coagulopathy in bites using snake ontogenetic parameters.基于蛇种进化参数预测蛇伤所致凝血功能障碍
Clin Toxicol (Phila). 2020 May;58(5):388-396. doi: 10.1080/15563650.2019.1648817. Epub 2019 Aug 6.
引用本文的文献
1
Dermatopathological findings of Bothrops atrox snakebites: A case series in the Brazilian Amazon.矛头蝮蛇咬伤的皮肤病理学发现：巴西亚马逊地区的病例系列
PLoS Negl Trop Dis. 2024 Dec 26;18(12):e0012704. doi: 10.1371/journal.pntd.0012704. eCollection 2024 Dec.
2
Compartment Syndrome Secondary to Bothrops spp. Envenomation in Triângulo Mineiro, Region, Minas Gerais, Brazil.巴西米纳斯吉拉斯州三角地区 Bothrops spp. 蛇咬伤致间隔综合征。
Rev Soc Bras Med Trop. 2023 Jul 24;56:e01302023. doi: 10.1590/0037-8682-0130-2023. eCollection 2023.
3
Children Growing Up with Severe Disabilities as a Result of Snakebite Envenomations in Indigenous Villages of the Brazilian Amazon: Three Cases and Narratives.儿童因在巴西亚马逊土著村庄被蛇咬伤而患有严重残疾：三个案例和叙述。
Toxins (Basel). 2023 May 23;15(6):352. doi: 10.3390/toxins15060352.
4
Pregnancy outcomes after snakebite envenomations: A retrospective cohort in the Brazilian Amazonia.巴西亚马逊地区蛇咬伤后的妊娠结局：一项回顾性队列研究。
PLoS Negl Trop Dis. 2022 Dec 5;16(12):e0010963. doi: 10.1371/journal.pntd.0010963. eCollection 2022 Dec.
5
Experimental Envenomation: Blood Plasma Proteome Effects after Local Tissue Damage and Perspectives on Thromboinflammation.实验性中毒：局部组织损伤后血浆蛋白质组学的影响及血栓炎症的观点。
Toxins (Basel). 2022 Sep 1;14(9):613. doi: 10.3390/toxins14090613.
6
CCL-2 and CXCL-8: Potential Prognostic Biomarkers of Acute Kidney Injury after a Snakebite.CCL-2 和 CXCL-8：蛇伤后急性肾损伤的潜在预后生物标志物。
Mediators Inflamm. 2022 Sep 7;2022:8285084. doi: 10.1155/2022/8285084. eCollection 2022.
7
: An Arboreal Pitviper in the Amazon and Atlantic Forest.亚马逊和大西洋森林中的树栖蝮蛇。
Front Immunol. 2021 Dec 15;12:778302. doi: 10.3389/fimmu.2021.778302. eCollection 2021.
本文引用的文献
1
, the most important snake involved in human envenomings in the amazon: How venomics contributes to the knowledge of snake biology and clinical toxinology.亚马逊地区导致人类中毒最重要的蛇类：毒液组学如何促进对蛇生物学和临床毒素学的认识。
Toxicon X. 2020 Apr 23;6:100037. doi: 10.1016/j.toxcx.2020.100037. eCollection 2020 Jun.
2
"": predicting venom-induced coagulopathy in bites using snake ontogenetic parameters.基于蛇种进化参数预测蛇伤所致凝血功能障碍
Clin Toxicol (Phila). 2020 May;58(5):388-396. doi: 10.1080/15563650.2019.1648817. Epub 2019 Aug 6.
3
Stepping into a dangerous quagmire: Macroecological determinants of Bothrops envenomings, Brazilian Amazon.步入危险的沼泽地：巴西亚马逊地区矛头蝮属蛇类咬伤的宏观生态学决定因素。
PLoS One. 2018 Dec 6;13(12):e0208532. doi: 10.1371/journal.pone.0208532. eCollection 2018.
4
Epidemiological study of snakebite cases in Brazilian Western Amazonia.巴西西部亚马逊地区蛇咬伤病例的流行病学研究。
Rev Soc Bras Med Trop. 2018 May-Jun;51(3):338-346. doi: 10.1590/0037-8682-0489-2017.
5
Snakebite envenoming.蛇咬伤中毒
Nat Rev Dis Primers. 2017 Oct 5;3:17079. doi: 10.1038/nrdp.2017.79.
6
Poor efficacy of preemptive amoxicillin clavulanate for preventing secondary infection from Bothrops snakebites in the Brazilian Amazon: A randomized controlled clinical trial.在巴西亚马逊地区，预防性使用阿莫西林克拉维酸对预防矛头蝮蛇咬伤继发感染疗效不佳：一项随机对照临床试验。
PLoS Negl Trop Dis. 2017 Jul 10;11(7):e0005745. doi: 10.1371/journal.pntd.0005745. eCollection 2017 Jul.
7
Snakebites as a largely neglected problem in the Brazilian Amazon: highlights of the epidemiological trends in the State of Amazonas.蛇咬伤在巴西亚马逊地区是一个很大程度上被忽视的问题：亚马孙州流行病学趋势要点
Rev Soc Bras Med Trop. 2015;48 Suppl 1:34-41. doi: 10.1590/0037-8682-0105-2013.
8
Snakebites and scorpion stings in the Brazilian Amazon: identifying research priorities for a largely neglected problem.巴西亚马逊地区的蛇咬伤和蝎子蜇伤：确定一个被严重忽视问题的研究重点
PLoS Negl Trop Dis. 2015 May 21;9(5):e0003701. doi: 10.1371/journal.pntd.0003701. eCollection 2015 May.
9
Snake envenoming: a disease of poverty.蛇伤：一种贫困病。
PLoS Negl Trop Dis. 2009 Dec 22;3(12):e569. doi: 10.1371/journal.pntd.0000569.
10
The global burden of snakebite: a literature analysis and modelling based on regional estimates of envenoming and deaths.蛇咬伤的全球负担：基于区域中毒和死亡估计的文献分析与建模
PLoS Med. 2008 Nov 4;5(11):e218. doi: 10.1371/journal.pmed.0050218.
Zotero 插件