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严重急性呼吸综合征冠状病毒 2(COVID-19):开始了解一种新病毒。

SARS-CoV-2 (COVID-19): Beginning to Understand a New Virus.

机构信息

Department of Industrial and Environmental Engineering, Graduate School of Environment, Gachon University, Seongnam-si, Gyeonggi-do, South Korea.

Department of Bionanotechnology, Gachon University, Seongnam-si, Gyeonggi-do, South Korea.

出版信息

Adv Exp Med Biol. 2021;1321:3-19. doi: 10.1007/978-3-030-59261-5_1.

Abstract

Within the last two decades, several members of the Coronaviridae family demonstrated epidemic potential. In late 2019, an unnamed genetic relative, later named SARS-CoV-2 (COVID-19), erupted in the highly populous neighborhoods of Wuhan, China. Unchecked, COVID-19 spread rapidly among interconnected communities and related households before containment measures could be enacted. At present, the mortality rate of COVID-19 infection worldwide is 6.6%. In order to mitigate the number of infections, restrictions or recommendations on the number of people that can gather in a given area have been employed by governments worldwide. For governments to confidently lift these restrictions as well as counter a potential secondary wave of infections, alternative medications and diagnostic strategies against COVID-19 are urgently required. This review has focused on these issues.

摘要

在过去的二十年中,冠状病毒科的几个成员表现出了流行潜力。2019 年末,一种未命名的遗传相关病毒,后来被命名为 SARS-CoV-2(COVID-19),在中国人口稠密的武汉市爆发。在采取控制措施之前,COVID-19 在相互关联的社区和相关家庭中迅速传播。目前,COVID-19 感染的全球死亡率为 6.6%。为了减少感染人数,世界各国政府都对在特定地区聚集的人数进行了限制或建议。为了让各国政府有信心解除这些限制并应对潜在的第二波感染,急需针对 COVID-19 的替代药物和诊断策略。本综述重点讨论了这些问题。

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