School of Psychology and Cognitive Science, East China Normal University, Shanghai, China.
School of Psychology, Shaanxi Normal University, Xi'an, China.
Psychiatry Res Neuroimaging. 2021 Apr 30;310:111269. doi: 10.1016/j.pscychresns.2021.111269. Epub 2021 Feb 22.
Internet gaming disorder (IGD) is becoming a prevalent mental health concern around the world. However, the relationship among brain gray matter volume (GMV), emotion induced by decision-making and the level of reflection in IGD participants has not been fully elucidated to date. The current study aimed to explore this issue by combining a sequential decision task and voxel-based morphometry. Twenty-six IGD participants and 28 demographically matched healthy controls were recruited. After collecting Rumination-Reflection questionnaire data and high-resolution T1-weighted MRI data, participants were asked to complete a sequential decision task. The results demonstrated that compared to healthy controls, IGD participants exhibited significantly decreased GMV in the superior frontal gyrus (SFG). Moreover, GMV in the SFG of IGD participants fully mediated the impact of reflection level on the emotion of loss outcome during the sequential decision task. These results indicate that IGD is associated with reduced GMV in the SFG, and this structural change in IGD contributes to a particular relationship between the level of reflection and regret emotion for loss outcome in the sequential decision task.
网络成瘾障碍（IGD）正在成为全球普遍存在的心理健康问题。然而，迄今为止，尚未充分阐明 IGD 参与者的大脑灰质体积（GMV）、决策引起的情绪和反省水平之间的关系。本研究旨在通过结合序列决策任务和基于体素的形态测量学来探讨这一问题。招募了 26 名 IGD 参与者和 28 名人口统计学匹配的健康对照组。在收集反刍-反思问卷数据和高分辨率 T1 加权 MRI 数据后，参与者被要求完成一个序列决策任务。结果表明，与健康对照组相比，IGD 参与者在前额上回（SFG）的 GMV 显著降低。此外，IGD 参与者 SFG 的 GMV 完全介导了在序列决策任务中，反省水平对损失结果情绪的影响。这些结果表明，IGD 与 SFG 中的 GMV 减少有关，而 IGD 中的这种结构变化导致了序列决策任务中反省水平和对损失结果的后悔情绪之间的特定关系。
