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从人类健康皮肤分离出的新细菌马赛-Q2068T菌株的基因组草图及描述

Draft genome and description of strain Marseille-Q2068T sp. nov., a new bacterium isolated from human healthy skin.

作者信息

Boxberger M, Ben Khedher M, Magnien S, Cassir N, La Scola B

机构信息

Aix-Marseille Université, IRD, AP-HM, MEPHI, Marseille, France.

IHU-Méditerranée Infection, Marseille, France.

出版信息

New Microbes New Infect. 2021 Jan 15;40:100839. doi: 10.1016/j.nmni.2021.100839. eCollection 2021 Mar.

Abstract

In 2019, by culturing a skin swab from the forehead of a 70-year-old healthy woman via the culturomics method, we isolated the new bacterial strain Marseille-Q2068T (= CSUR-Q2068). Matrix-assisted desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) failed to identify this isolate. Analysis of the 16S ribosomal RNA gene and genome-to-genome comparison suggested that this taxon belongs to a novel bacterial species within the family in the phylum Proteobacteria. We describe here its main phenotypic characteristics, genome sequence and annotation of strain Marseille-Q2068T, a new member of the genus, which we propose as the type strain.

摘要

2019年,我们通过宏基因组学方法培养了一名70岁健康女性前额的皮肤拭子,分离出了新的细菌菌株马赛-Q2068T(=CSUR-Q2068)。基质辅助激光解吸电离飞行时间质谱(MALDI-TOF MS)未能鉴定出该分离株。对16S核糖体RNA基因的分析和全基因组比较表明,该分类单元属于变形菌门中一个新的细菌物种。我们在此描述了马赛-Q2068T菌株的主要表型特征、基因组序列和注释,它是该属的一个新成员,我们提议将其作为模式菌株。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ee9/7890426/904e0dbf32b1/gr1.jpg

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