Ramlucken Uraisha, Ramchuran Santosh O, Moonsamy Ghaneshree, Jansen van Rensburg Christine, Thantsha Mapitsi S, Lalloo Rajesh
The Council for Scientific and Industrial Research, Pretoria, 0001, South Africa.
Department of Biochemistry, Genetics and Microbiology, University of Pretoria, Pretoria, South Africa.
Biotechnol Rep (Amst). 2020 Dec 31;29:e00575. doi: 10.1016/j.btre.2020.e00575. eCollection 2021 Mar.
Probiotics can be effective alternatives to the prophylactic use of antibiotic growth promoters (AGPs) in response to industry and consumer concerns around their use in poultry. Studies on the suitability of probiotics are emerging and showing benefits, but information on the production technology is limited. We developed the production process for a novel probiotic product previously shown to be effective in field trials. All strains were cultivated to a spore concentration exceeding 1 × 10 CFU. mL. The spores of each strain were harvested, processed into a powder intermediate and formulated into an end product with 100 % recoveries and a shelf life stability >1 year. The probiotic was shown to be incorporated into broiler feed exceeding the desired concentration of 1 × 10 CFU. g. Using efficient process technology and lower cost materials, this study presents a commercially relevant case for the potential adoption of probiotic products by the poultry industry.
由于行业和消费者对家禽使用抗生素生长促进剂(AGPs)存在担忧,益生菌可作为预防性使用AGPs的有效替代品。关于益生菌适用性的研究不断涌现并显示出益处,但有关生产技术的信息有限。我们开发了一种新型益生菌产品的生产工艺,该产品先前已在田间试验中证明有效。所有菌株均培养至孢子浓度超过1×10 CFU/mL。收获每个菌株的孢子,加工成粉末中间体,并配制成终产品,回收率达100%,保质期稳定性>1年。结果表明,该益生菌添加到肉鸡饲料中的浓度超过了所需的1×10 CFU/g。本研究采用高效的工艺技术和低成本的材料,为家禽业采用益生菌产品提供了一个具有商业相关性的案例。