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前庭性偏头痛:前庭疾病中的变色龙。

Vestibular migraine: the chameleon in vestibular disease.

机构信息

Department of Neurology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.

出版信息

Neurol Sci. 2021 May;42(5):1719-1731. doi: 10.1007/s10072-021-05133-1. Epub 2021 Mar 5.

DOI:10.1007/s10072-021-05133-1
PMID:33666767
Abstract

Vestibular migraine (VM) has been recently receiving increasing attention as an independent disease concept. It is a common cause of dizziness or headache; however, it was not clearly defined until 2018. Its diagnosis mainly relies on clinical history, including vertigo and migraine, as indicated by the appendix of the 3 edition of the International Classification Diagnostic Criteria for Headache Diseases. There is often an overlap of vertigo and migraine across vestibular diseases; therefore, VM often imitates various vestibular diseases. Additionally, VM lacks specific laboratory biomarkers; therefore, it has high misdiagnosis and missed diagnosis rates. Therefore, numerous clinical patients could have inaccurate diagnoses and improper treatment. Therefore, there is a need for further basic research to further clarify the pathogenesis. Moreover, there is a need for clinical trials focusing on specific laboratory biomarkers, including serological, radiological, and electrophysiological examinations, to develop more detailed and complete diagnostic criteria.

摘要

前庭性偏头痛(VM)作为一个独立的疾病概念,最近受到越来越多的关注。它是头晕或头痛的常见原因;然而,直到 2018 年才明确定义。其诊断主要依赖于临床病史,包括眩晕和偏头痛,这在头痛疾病的国际分类诊断标准第三版附录中有说明。在各种前庭疾病中,眩晕和偏头痛常常重叠;因此,VM 常常模仿各种前庭疾病。此外,VM 缺乏特异性的实验室生物标志物;因此,它的误诊和漏诊率很高。因此,许多临床患者可能会被误诊,治疗不当。因此,需要进一步的基础研究来进一步阐明发病机制。此外,还需要针对特定的实验室生物标志物(包括血清学、影像学和电生理学检查)进行临床试验,以制定更详细和完整的诊断标准。

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J Clin Med. 2025 Jul 8;14(14):4828. doi: 10.3390/jcm14144828.
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Vestibular migraine: an update.前庭性偏头痛:最新研究进展。
Curr Opin Neurol. 2024 Jun 1;37(3):252-263. doi: 10.1097/WCO.0000000000001257. Epub 2024 Apr 15.
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Cognition in vestibular disorders: state of the field, challenges, and priorities for the future.前庭疾病中的认知:该领域的现状、挑战及未来重点

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Vestibular migraine treatment and prevention.前庭性偏头痛的治疗与预防。
HNO. 2019 Jun;67(6):425-428. doi: 10.1007/s00106-019-0661-3.
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Abnormal visuo-vestibular interactions in vestibular migraine: a cross sectional study.前庭性偏头痛患者视-前庭相互作用异常:一项横断面研究。
Brain. 2019 Mar 1;142(3):606-616. doi: 10.1093/brain/awy355.
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The Spectrum of Vestibular Migraine: Clinical Features, Triggers, and Examination Findings.前庭性偏头痛的谱系:临床特征、诱因和检查结果。
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Can a Chronic BPPV With a History of Trauma be the Trigger of Symptoms in Vestibular Migraine, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), and Whiplash Associated Disorders (WAD)? A Retrospective Cohort Study.有创伤史的慢性 BPPV 是否会引发前庭性偏头痛、肌痛性脑脊髓炎/慢性疲劳综合征 (ME/CFS) 和挥鞭样损伤相关疾病 (WAD) 的症状?一项回顾性队列研究。
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