Department of Neurology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.
Neurol Sci. 2021 May;42(5):1719-1731. doi: 10.1007/s10072-021-05133-1. Epub 2021 Mar 5.
Vestibular migraine (VM) has been recently receiving increasing attention as an independent disease concept. It is a common cause of dizziness or headache; however, it was not clearly defined until 2018. Its diagnosis mainly relies on clinical history, including vertigo and migraine, as indicated by the appendix of the 3 edition of the International Classification Diagnostic Criteria for Headache Diseases. There is often an overlap of vertigo and migraine across vestibular diseases; therefore, VM often imitates various vestibular diseases. Additionally, VM lacks specific laboratory biomarkers; therefore, it has high misdiagnosis and missed diagnosis rates. Therefore, numerous clinical patients could have inaccurate diagnoses and improper treatment. Therefore, there is a need for further basic research to further clarify the pathogenesis. Moreover, there is a need for clinical trials focusing on specific laboratory biomarkers, including serological, radiological, and electrophysiological examinations, to develop more detailed and complete diagnostic criteria.
前庭性偏头痛(VM)作为一个独立的疾病概念,最近受到越来越多的关注。它是头晕或头痛的常见原因;然而,直到 2018 年才明确定义。其诊断主要依赖于临床病史,包括眩晕和偏头痛,这在头痛疾病的国际分类诊断标准第三版附录中有说明。在各种前庭疾病中,眩晕和偏头痛常常重叠;因此,VM 常常模仿各种前庭疾病。此外,VM 缺乏特异性的实验室生物标志物;因此,它的误诊和漏诊率很高。因此,许多临床患者可能会被误诊,治疗不当。因此,需要进一步的基础研究来进一步阐明发病机制。此外,还需要针对特定的实验室生物标志物(包括血清学、影像学和电生理学检查)进行临床试验,以制定更详细和完整的诊断标准。