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使用食品级聚合物的用于粉末和病毒安全防护的3D打印口罩：实证测试

3D Printed Masks for Powders and Viruses Safety Protection Using Food Grade Polymers: Empirical Tests.

作者信息

Foresti Ruben, Ghezzi Benedetta, Vettori Matteo, Bergonzi Lorenzo, Attolino Silvia, Rossi Stefano, Tarabella Giuseppe, Vurro Davide, von Zeppelin Didier, Iannotta Salvatore, Zappettini Andrea, Macaluso Guido Maria, Miragoli Michele, Maggio Marcello Giuseppe, Costantino Cosimo, Selleri Stefano, Macaluso Claudio

机构信息

Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.

Center of Dental Medicine, University of Parma, 43126 Parma, Italy.

出版信息

Polymers (Basel). 2021 Feb 18;13(4):617. doi: 10.3390/polym13040617.

DOI:10.3390/polym13040617
PMID:33670792
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7923032/
Abstract

The production of 3D printed safety protection devices (SPD) requires particular attention to the material selection and to the evaluation of mechanical resistance, biological safety and surface roughness related to the accumulation of bacteria and viruses. We explored the possibility to adopt additive manufacturing technologies for the production of respirator masks, responding to the sudden demand of SPDs caused by the emergency scenario of the pandemic spread of SARS-COV-2. In this study, we developed different prototypes of masks, exclusively applying basic additive manufacturing technologies like fused deposition modeling (FDM) and droplet-based precision extrusion deposition (db-PED) to common food packaging materials. We analyzed the resulting mechanical characteristics, biological safety (cell adhesion and viability), surface roughness and resistance to dissolution, before and after the cleaning and disinfection phases. We showed that masks 3D printed with home-grade printing equipment have similar performances compared to the industrial-grade ones, and furthermore we obtained a perfect face fit by customizing their shape. Finally, we developed novel approaches to the additive manufacturing post-processing phases essential to assure human safety in the production of 3D printed custom medical devices.

摘要

3D打印安全防护设备（SPD）的生产需要特别关注材料选择以及与细菌和病毒积聚相关的机械抗性、生物安全性和表面粗糙度评估。我们探索了采用增材制造技术生产呼吸面罩的可能性，以应对由SARS-CoV-2大流行传播的紧急情况导致的对SPD的突然需求。在本研究中，我们开发了不同的面罩原型，仅将诸如熔融沉积建模（FDM）和基于液滴的精密挤出沉积（db-PED）等基本增材制造技术应用于普通食品包装材料。我们分析了在清洁和消毒阶段前后所得产品的机械特性、生物安全性（细胞粘附和活力）、表面粗糙度和耐溶解性。我们表明，用家用级打印设备3D打印的面罩与工业级面罩具有相似的性能，此外，通过定制其形状我们获得了完美的面部贴合度。最后，我们开发了新颖的增材制造后处理阶段方法，这对于确保3D打印定制医疗设备生产中的人员安全至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce3f/7923032/aef2f4f6c050/polymers-13-00617-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce3f/7923032/f312b7ce4137/polymers-13-00617-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce3f/7923032/77f038b4fb12/polymers-13-00617-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce3f/7923032/9bf7a839fbc8/polymers-13-00617-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce3f/7923032/015af9f026af/polymers-13-00617-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce3f/7923032/aef2f4f6c050/polymers-13-00617-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce3f/7923032/f312b7ce4137/polymers-13-00617-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce3f/7923032/77f038b4fb12/polymers-13-00617-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce3f/7923032/9bf7a839fbc8/polymers-13-00617-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce3f/7923032/015af9f026af/polymers-13-00617-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce3f/7923032/aef2f4f6c050/polymers-13-00617-g005.jpg

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