Bioengineering Laboratory, Higher National School of Biotechnology, Constantine 25016, Algeria.
Faculty of Medicine, Transilvania University of Brasov, 500039 Brasov, Romania.
Sensors (Basel). 2021 Feb 20;21(4):1485. doi: 10.3390/s21041485.
Despite barrier measures and physical distancing tailored by the populations worldwide, coronavirus continues to spread causing severe health and social-economic problems. Therefore, researchers are focusing on developing efficient detection and therapeutic platforms for SARS-CoV2. In this context, various biotechnologies, based on novel molecules targeting the virus with high specificity and affinity, have been described. In parallel, new approaches exploring nanotechnology have been proposed for enhancing treatments and diagnosis. We discuss in the first part of this review paper, the different biosensing and rapid tests based on antibodies, nucleic acids and peptide probes described since the beginning of the pandemic. Furthermore, given their numerous advantages, the contribution of nanotechnologies is also highlighted.
尽管世界各地的人们都采取了障碍措施和保持身体距离，但冠状病毒仍在继续传播，造成严重的健康和社会经济问题。因此，研究人员专注于开发针对 SARS-CoV2 的高效检测和治疗平台。在这种情况下，已经描述了基于针对病毒具有高特异性和亲和力的新型分子的各种生物技术。同时，还提出了利用纳米技术的新方法来增强治疗和诊断。在本文的第一部分中，我们讨论了自疫情开始以来描述的基于抗体、核酸和肽探针的不同生物传感和快速检测方法。此外，鉴于它们的众多优势，还强调了纳米技术的贡献。
