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杏仁的摄入增加了健康亚洲女性对 UVB 的抵抗力。

Almond consumption increased UVB resistance in healthy Asian women.

机构信息

Department of Medicine, David Geffen School of Medicine, Center for Human Nutrition, Los Angeles, CA, USA.

Division of Dermatology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.

出版信息

J Cosmet Dermatol. 2021 Sep;20(9):2975-2980. doi: 10.1111/jocd.13946. Epub 2021 Jan 24.

Abstract

BACKGROUND

Almonds are a rich source of phenolic and polyphenolic compounds, which have antioxidant activity. In vitro and in vivo studies have demonstrated that topical application of almond oil and almond skin extract reduces UVB-induced photoaging. Ultraviolet-B (UVB) protection by oral almond consumption has not been previously studied in humans.

OBJECTIVES

To investigate whether oral almond consumption can increase resistance to UVB radiation and reduce skin aging in healthy Asian women.

METHODS

Thirty-nine female participants (18-45 years) with Fitzpatrick skin type II-IV were randomly assigned to consume either 1.5 oz of almonds or 1.8 oz of pretzels daily for 12 weeks. Minimal erythema dose (MED) was determined using a standardized protocol, which determined the minimal radiation needed to induce erythema on the inner arm following UVB exposure. Facial skin texture was evaluated by two dermatologists using the Clinician's Erythema Assessment scale and Allergan Roughness scale. Facial melanin index, hydration, sebum, and erythema were determined using a cutometer.

RESULTS

The MED was increased in the subjects consuming almonds compared to the control group consuming pretzels. There were no differences noted between the groups consuming almonds versus pretzels in Allergan roughness, melanin, hydration, or sebum on facial skin.

CONCLUSIONS

Our findings suggest that daily oral almond consumption may lead to enhanced protection from UV photodamage by increasing the MED.

摘要

背景

杏仁是酚类和多酚类化合物的丰富来源,具有抗氧化活性。体外和体内研究表明,杏仁油和杏仁皮提取物的局部应用可减少 UVB 诱导的光老化。以前尚未在人类中研究过口服杏仁消费对 UVB 的保护作用。

目的

研究口服杏仁消费是否可以增加对 UVB 辐射的抵抗力并减少健康亚洲女性的皮肤衰老。

方法

39 名女性参与者(18-45 岁),皮肤类型为 Fitzpatrick II-IV,随机分为每天食用 1.5 盎司杏仁或 1.8 盎司椒盐脆饼 12 周。使用标准化方案确定最小红斑剂量(MED),该方案确定了在 UVB 暴露后内臂上引起红斑所需的最小辐射。两位皮肤科医生使用临床医生的红斑评估量表和 Allergan 粗糙度量表评估面部皮肤纹理。使用皮肤折射仪评估面部黑色素指数、水分、皮脂和红斑。

结果

与食用椒盐脆饼的对照组相比,食用杏仁的受试者的 MED 增加。食用杏仁与食用椒盐脆饼的组之间在面部皮肤的 Allergan 粗糙度、黑色素、水分或皮脂方面没有差异。

结论

我们的研究结果表明,每天口服杏仁消费可能通过增加 MED 来提供增强的 UV 光损伤防护。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64ce/8451851/7dec7a94e2e3/JOCD-20-2975-g002.jpg

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