Cutrale Perioperative and Ageing Group, Department of Bioengineering, Imperial College London, London, United Kingdom.
The Wellington Hospital, Circus Road, St John's Wood, London, United Kingdom.
J Infect Dis. 2021 May 28;223(10):1671-1676. doi: 10.1093/infdis/jiab120.
It is currently unknown how post-COVID-19 syndrome (PCS) may affect those infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This longitudinal study includes healthcare staff who tested positive for SARS-CoV-2 between March and April 2020, with follow-up of their antibody titers and symptoms. More than half (21 of 38) had PCS after 7-8 months. There was no statistically significant difference between initial reverse-transcription polymerase chain reaction titers or serial antibody levels between those who did and those who did not develop PCS. This study highlights the relative commonality of PCS in healthcare workers and this should be considered in vaccination scheduling and workforce planning to allow adequate frontline staffing numbers.
目前尚不清楚新冠病毒后综合征(PCS)会如何影响那些感染严重急性呼吸综合征冠状病毒 2 型(SARS-CoV-2)的人。这项纵向研究包括了 2020 年 3 月至 4 月期间检测出 SARS-CoV-2 呈阳性的医护人员,对他们的抗体滴度和症状进行了随访。超过一半(38 人中有 21 人)在 7-8 个月后出现了 PCS。在那些出现和未出现 PCS 的人群之间,初始逆转录聚合酶链反应滴度或连续抗体水平之间没有统计学上的显著差异。这项研究强调了医护人员中 PCS 的相对普遍性,这在制定疫苗接种计划和劳动力规划时应加以考虑,以确保有足够的一线人员数量。