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佛得角糖尿病患病率及其相关因素:对2020年世界卫生组织非传染性疾病危险因素全球健康调查(STEPS)的分析

Prevalence of diabetes and its associated factors in Cape Verde: an analysis of the 2020 WHO STEPS survey on non-communicable diseases risk factors.

作者信息

Okyere Joshua, Ayebeng Castro, Dickson Kwamena Sekyi

机构信息

Department of Population and Health, University of Cape Coast, Cape Coast, Ghana.

School of Human and Health Sciences, University of Huddersfield, Queensgate, Huddersfield, England, United Kingdom.

出版信息

BMC Endocr Disord. 2024 Dec 18;24(1):264. doi: 10.1186/s12902-024-01803-1.

Abstract

BACKGROUND

Type 2 diabetes mellitus (T2DM) represents a significant global health challenge, with its prevalence steadily rising across diverse populations. Understanding the factors associated with T2DM is crucial for effective prevention and management strategies. In Cape Verde, an archipelago nation off the coast of West Africa, the burden of T2DM is of particular concern, yet comprehensive studies investigating its determinants in this context remain sparse. This study aims to narrow the knowledge gap by assessing the prevalence of prediabetes, T2DM and its associated factors among the adult Cape Verdean population.

METHODS

Data from the WHO STEPs survey were used. We analyzed data from 1,936 adults aged 18-69 years. The outcome variable was diabetes status computed using the fasting blood glucose (mg/dl). The data was weighted before the analysis to account for sampling biases. Multinomial logistic regression models were computed in STATA version 18.

RESULTS

The overall prevalence of prediabetes and T2DM was 7.8% (95% CI: 6.1-9.9) and 3.9% (95% CI: 3.1-4.9), respectively. Increasing age was associated with a higher odd of prediabetes and T2DM with the highest odds observed among older adults [(prediabetes: AORs = 3.20, 95%CI: 1.88-5.54) and T2DM: AOR = 3.51, 95%CI: 1.71-7.18)]. Additionally, high total cholesterol levels were linked to increased odds of T2DM (AOR = 2.48, 95%CI: 1.64-3.76). Individuals who consumed less than four servings of vegetables daily had higher odds of T2DM (AOR = 1.74, 95%CI: 1.12-2.71) while being overweight/obese was associated with higher odds of prediabetes (AOR = 1.57, 95%CI: 1.10-2.23). Urban residents had higher odds of T2DM than rural residents (AOR = 1.92, 95%CI: 1.23-3.00). Also, higher educational attainment was associated with lower odds of T2DM only (AOR = 0.33, 95%CI: 0.12-0.88) but not statistically significant for prediabetes.

CONCLUSION

Based on the findings, we conclude that ageing, overweight/obesity, vegetable consumption and total cholesterol level are important predictors of pre-diabetes and T2DM in Cape Verde. As such, weight management and cholesterol management should be integral parts of T2DM prevention strategies. Additionally, clinicians and diabetes societies in Cape Verde must make the promotion of vegetable consumption a key component of their health advice and advocacy.

CLINICAL TRIAL NUMBER

Not applicable.

摘要

背景

2型糖尿病(T2DM)是一项重大的全球健康挑战,其在不同人群中的患病率稳步上升。了解与T2DM相关的因素对于有效的预防和管理策略至关重要。佛得角是西非海岸的一个群岛国家,T2DM的负担尤其令人担忧,但在这种背景下调查其决定因素的全面研究仍然很少。本研究旨在通过评估佛得角成年人群中糖尿病前期、T2DM的患病率及其相关因素来缩小知识差距。

方法

使用了世界卫生组织(WHO)的全球健康危险因素调查(STEPS)数据。我们分析了1936名年龄在18 - 69岁之间的成年人的数据。结果变量是使用空腹血糖(mg/dl)计算的糖尿病状态。在分析之前对数据进行加权以考虑抽样偏差。在STATA 18版本中计算多项逻辑回归模型。

结果

糖尿病前期和T2DM的总体患病率分别为7.8%(95%置信区间:6.1 - 9.9)和3.9%(95%置信区间:3.1 - 4.9)。年龄增长与糖尿病前期和T2DM的较高几率相关,在老年人中观察到的几率最高[(糖尿病前期:调整后的比值比(AORs)= 3.20,95%置信区间:1.88 - 5.54)和T2DM:AOR = 3.51,95%置信区间:1.71 - 7.18)]。此外,高总胆固醇水平与T2DM几率增加有关(AOR = 2.48,95%置信区间:1.64 - 3.76)。每天食用蔬菜少于四份的个体患T2DM的几率更高(AOR = 1.74,95%置信区间:1.12 - 2.71),而超重/肥胖与糖尿病前期的较高几率相关(AOR = 1.57,95%置信区间:1.10 - 2.23)。城市居民患T2DM的几率高于农村居民(AOR = 1.92,95%置信区间:1.23 - 3.00)。此外,较高的教育程度仅与较低的T2DM几率相关(AOR = 0.33,95%置信区间:0.12 - 0.88),但对糖尿病前期无统计学意义。

结论

基于这些发现,我们得出结论,年龄增长、超重/肥胖、蔬菜消费和总胆固醇水平是佛得角糖尿病前期和T2DM的重要预测因素。因此,体重管理和胆固醇管理应成为T2DM预防策略的组成部分。此外,佛得角的临床医生和糖尿病协会必须将促进蔬菜消费作为其健康建议和宣传的关键组成部分。

临床试验编号

不适用。

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