Department of Forensic Science, School of Basic Medical Sciences, Central South University, No:172, Tongzipo Road, Changsha, 410013, Hunan, People's Republic of China.
Laboratory of Molecular Biology and Genetics (LMBG), University Joseph KI - ZERBO, CERBA/LABIOGENE, Ouagadougou 01, 01 BP: 364, Burkina Faso.
Int J Legal Med. 2021 Sep;135(5):1767-1769. doi: 10.1007/s00414-021-02544-9. Epub 2021 Mar 6.
Burkina Faso (BF) is a landlocked Sahelian country located in the middle of West Africa. Sixty-three local languages are spoken in BF. Despite this high diversity, the BF population remains poorly investigated, and updated forensic parameters with a large number of Y chromosome short tandem repeats (Y-STRs) are still missing. Herein, 447 DNA samples were typed for a cocktail of 29 Y-STR loci. None of these 447 individuals in total shared a common haplotype. The overall Y-STR haplotypes were successfully uploaded online on the Y-STR Haplotype Reference Database (YHRD) with the accession numbers YA004690 and YA004691. The main haplotype diversity was 0.9999999965, which is much higher than that obtained with 12 Y-STRs in a previous study. Haploid Match Probability for the whole dataset was 0.002237. The phylogenetic analysis of 24 ethnic groups of BF shows that the ethnic group named BISSA is closer to Gur speakers than Mande speakers, where they belong. In addition, genetic structure analysis of 49 African subpopulations sheds light on the fact that geographic proximity turns out to be one of the best predictors of genetic affinity between populations.
布基纳法索（BF）是一个位于西非中部的内陆萨赫勒国家。BF 有 63 种当地语言。尽管存在如此高的多样性，但 BF 人口仍未得到充分研究，并且仍缺少经过更新的具有大量 Y 染色体短串联重复（Y-STR）的法医参数。在此，对 447 份 DNA 样本进行了 29 个 Y-STR 基因座的混合分型。在总共 447 个人中，没有一个人共享共同的单倍型。这些 Y-STR 单倍型已成功上传至 Y-STR 单倍型参考数据库（YHRD），登录号为 YA004690 和 YA004691。主要的 Y-STR 单倍型多样性为 0.9999999965，远高于之前研究中使用 12 个 Y-STR 获得的结果。整个数据集的单倍型匹配概率为 0.002237。对 BF 的 24 个族群的系统发生分析表明，名为 BISSA 的族群与 Gur 语族群的亲缘关系比与他们所属的曼德语族群的亲缘关系更近。此外，对 49 个非洲亚群的遗传结构分析表明，地理接近是人群之间遗传亲和力的最佳预测因素之一。
