Boronat Susana
Pediatric Neurology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Front Neurol. 2021 Feb 18;11:613832. doi: 10.3389/fneur.2020.613832. eCollection 2020.
Most children with SARS-CoV-2 infection have relatively mild clinical symptoms without fever or pneumonia, although severe cases with multiple-organ failure have been reported. Neurological symptoms, which have been mainly reported in adults, are very rare in children. This article will review 2 different aspects of neurological involvement related to this infection in children. In the first part, we will review the neurological abnormalities reported in children caused by this viral infection. Adults frequently report muscle pain, headache, anosmia, dysgeusia, and occasionally more severe central or peripheral nervous system damage. Neurological involvement seems infrequent in children, although some cases have been reported. In the second part, we will discuss the COVID-19 pandemic impact on the healthcare system of some countries, causing collateral damage to general pediatric care and in particular to those children affected with chronic diseases, mainly neurological conditions, including autism, intellectual disability, attention deficit and hyperactivity disorder (ADHD), neuromuscular disorders, cerebral palsy, and epilepsy, and patients needing neurosurgical procedures.
大多数感染新冠病毒的儿童临床症状相对较轻,无发热或肺炎症状,不过也有严重病例出现多器官功能衰竭的报道。主要在成人中报道的神经症状在儿童中非常罕见。本文将综述儿童感染新冠病毒后神经受累的两个不同方面。第一部分,我们将回顾由这种病毒感染导致的儿童神经异常情况。成人经常报告肌肉疼痛、头痛、嗅觉丧失、味觉障碍,偶尔还会出现更严重的中枢或周围神经系统损伤。尽管已有一些病例报道,但儿童神经受累似乎并不常见。第二部分,我们将讨论新冠疫情对一些国家医疗系统的影响,这对普通儿科护理造成了附带损害,尤其是对那些患有慢性疾病(主要是神经疾病,包括自闭症、智力残疾、注意力缺陷多动障碍(ADHD)、神经肌肉疾病、脑瘫和癫痫)的儿童以及需要进行神经外科手术的患者。