通过双平行光学相干断层扫描（OCT）传感器引导的手持式智能注射器进行斜向注射深度校正。
Oblique injection depth correction by a two parallel OCT sensor guided handheld SMART injector.
作者信息
Im Jintaek, Song Cheol
机构信息
Department of Robotics Engineering, DGIST, 333 Techno Jungang-Daero, Daegu, 42988, Republic of Korea.
出版信息
Biomed Opt Express. 2021 Jan 19;12(2):926-939. doi: 10.1364/BOE.410492. eCollection 2021 Feb 1.
Abstract
We present a SMART injector with two parallel common-path optical coherence tomography fibers to enable angle measurements and injection depth corrections for oblique subretinal injection. The two optical fibers are attached to opposite sides of a 33 G needle with known offsets and designed to pass through a 23 G trocar that has an inner diameter of 0.65 mm. By attaching a SMART system to a rotational stage, the measured angles are calibrated for minimal error from reference angles. A commercial eye model was used to evaluate the control performance, and injection experiments were performed on a phantom made of agarose gel and a porcine eye.
摘要
我们展示了一种智能注射器，它带有两根平行的共光路光学相干断层扫描光纤，用于实现斜向视网膜下注射的角度测量和注射深度校正。这两根光纤附着在一根33G针的相对两侧，具有已知的偏移量，并设计为穿过内径为0.65mm的23G套管针。通过将智能系统连接到旋转平台，对测量角度进行校准，使其与参考角度的误差最小。使用商业眼模型评估控制性能，并在由琼脂糖凝胶制成的模型和猪眼上进行注射实验。
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