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后路枕颈减压融合术治疗基底凹陷症的手术疗效:一项前瞻性研究。

Surgical outcomes of posterior occipito-cervical decompression and fusion for basilar invagination: A prospective study.

作者信息

Patel Ruchir, Solanki Anil M, Acharya Apurv

机构信息

Department of Orthopedics, B. J. Medical College, Civil Hospital, Asarwa, Ahmedabad, Gujarat, 380016, India.

出版信息

J Clin Orthop Trauma. 2020 Nov 27;13:127-133. doi: 10.1016/j.jcot.2020.11.016. eCollection 2021 Feb.

Abstract

STUDY DESIGN

A Prospective Study.

OBJECTIVE

To assess results of posterior occipito-cervical decompression and fusion operated with intra-operative traction/manipulation and instrumented reduction in cases of Basilar Invagination(BI).

METHODS

Total 22 patients of 8-65 years with diagnosed BI were operated for posterior occipito-cervical fusion by intra-operative traction/manipulation and instrumented reduction. Fusion was done using autologous bone graft taken from iliac crest. Immediate post-operative, first month and then every 3 months' follow-up examination were done for minimum period of 2 years.

RESULTS

22 patients (10 males,12 females) with mean age of 23.9 years having BI were included. 11 patients had C1 occipitalization, 4 had platybasia and 9 had atlanto-axial dislocation (AAD). 1 patient with os odontoideum with kyphotic deformity expired on 4th postoperative day due to respiratory insufficiency (mortality rate 4.54%). Neurological improvement by at least by one grade according to RANAWAT's and/or NURICK'S scale was observed in 17/21 patients (80.95%). 3 patients remained static and 1 had neuro-worsening. Mean mJOA score of 13.14 improved to 16.24. All had reduction of dens below foramen magnum according to McRae, chamberlain line and Ranawat index. Bone graft fused in all patients as confirmed with CT scan and dynamic X-rays. 1 wound dehiscence and 1 asymptomatic implant loosening were seen on follow-up.

CONCLUSION

Surgical treatment of BI with intra-operative traction/manipulation, instrumented reduction and posterior occipito-cervical fusion can achieve good correction of radiology, functional performance and clinical neurology as well as excellent fusion rates without adverse effects of trans-oral surgery.

摘要

研究设计

前瞻性研究。

目的

评估在基底凹陷症(BI)病例中,采用术中牵引/手法复位及器械复位进行枕颈后路减压融合术的效果。

方法

对22例年龄在8至65岁、诊断为BI的患者,采用术中牵引/手法复位及器械复位进行枕颈后路融合术。使用取自髂嵴的自体骨移植进行融合。术后即刻、术后第1个月,然后每3个月进行随访检查,最短随访2年。

结果

纳入22例平均年龄23.9岁的BI患者(男性10例,女性12例)。11例患者存在C1枕化,4例患者存在扁平颅底,9例患者存在寰枢椎脱位(AAD)。1例齿突骨并伴有后凸畸形的患者术后第4天因呼吸功能不全死亡(死亡率4.54%)。根据Ranawat和/或Nurick量表,17/21例患者(80.95%)神经功能至少改善1级。3例患者病情无变化,1例患者神经功能恶化。平均mJOA评分从13.14提高到16.24。根据McRae、Chamberlain线和Ranawat指数,所有患者的齿状突均低于枕大孔。CT扫描和动态X线证实所有患者骨移植均已融合。随访中发现1例伤口裂开和1例无症状的植入物松动。

结论

采用术中牵引/手法复位、器械复位及枕颈后路融合术治疗BI,可在放射学、功能表现和临床神经学方面实现良好矫正,融合率高,且无经口手术的不良反应。

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