Xin Hualei, Yang Yichao, Jiang Zhihua, Qian Menbao, Chen Yingdan, Li Shizhu, Cowling Benjamin J, Sun Junling, Li Zhongjie
Key Laboratory of Surveillance and Early Warning on Infectious Disease, Division of Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing, China.
WHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China.
Food Waterborne Parasitol. 2021 Jan 8;22:e00109. doi: 10.1016/j.fawpar.2020.e00109. eCollection 2021 Mar.
To effectively promote the implementation of interventions, the identification of high-risk groups and the characteristics of infection in endemic regions are needed. In a clonorchiasis-endemic area, local residents were randomly enrolled for helminth egg examination in June 2016. The prevalence in subpopulations as well as the knowledge, attitudes, and behaviours and the factors influencing clonorchiasis in egg-positive populations were analysed. A total of 2282 local residents participated in the survey; the prevalence was 48.6% (1109 persons). A higher prevalence was found in males (62.6%) than in females (29.7%). People older than 30 years had the highest prevalence (52.7%-57.6%). Among the 888 persons who were infected with and participated the questionnaire investigation, 19.0% (169/888) knew that it could cause cancer. In addition, 60.6% of people reported that they intended to keep eating raw fish despite knowing the risk of infection. The two primary reasons for continuing to eat raw fish were the disease being regarded as not serious (38.3%) and the belief that anti-parasite medications are effective (39.6%). A total of 94.4% (797/844) of responders reported eating raw fish more frequently in the home than outside of the home. Our study revealed a notably high prevalence in the study area. Awareness of clonorchiasis disease severity should be increased among high-risk individuals and families in highly endemic areas.
为有效促进干预措施的实施，需要确定流行地区的高危人群和感染特征。在一个华支睾吸虫病流行地区，于2016年6月随机招募当地居民进行蠕虫卵检查。分析了亚人群中的患病率以及虫卵阳性人群对华支睾吸虫病的知识、态度和行为及其影响因素。共有2282名当地居民参与了调查；患病率为48.6%（1109人）。男性患病率（62.6%）高于女性（29.7%）。30岁以上人群患病率最高（52.7%-57.6%）。在888名感染并参与问卷调查的人中，19.0%（169/888）知道该病可致癌。此外，60.6%的人报告称，尽管知道感染风险，但他们仍打算继续食用生鱼。继续食用生鱼的两个主要原因是认为该病不严重（38.3%）以及相信抗寄生虫药物有效（39.6%）。共有94.4%（797/844）的受访者报告称，在家中食用生鱼的频率高于在家外。我们的研究显示该研究地区的患病率显著较高。在高度流行地区的高危个体和家庭中，应提高对华支睾吸虫病疾病严重性的认识。
