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甲状腺功能亢进性淡漠性脑病:Wernicke 脑病和渗透性脱髓鞘综合征的不常见病因。

Apathetic encephalopathy in thyreotoxicosis: an unsual cause of wernicke encephalopathy and osmotic demyelinating syndrome.

机构信息

Neurology Department, Parma Hospital.

Neurology Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy.

出版信息

Acta Biomed. 2021 Feb 5;92(1):e2021055. doi: 10.23750/abm.v92i1.9473.

DOI:10.23750/abm.v92i1.9473
PMID:33682841
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7975956/
Abstract

Non-alcoholic Wernicke Encephalopathy (WE) is an overlooked complication of malnourishment in all its forms including undernutrition, inadequate vitamine intake and endocrinological diseases. Both delay in treatment and overtreatment can lead to severe neurological life-long consequences. Inadequate management in patients with chronic malnutrition may cause abrupt osmolytes unbalance and subsequent osmotic demyelination syndromes.  We describe a 65-year old man with apathetic encephalopathy caused by thyreotoxicosis and associated with malnutrition and severe thiamine depletion.

摘要

非酒精性 Wernicke 脑病(WE)是一种易被忽视的营养不良并发症,包括营养不足、维生素摄入不足和内分泌疾病。治疗延误和过度治疗都会导致严重的神经终身后果。慢性营养不良患者管理不当可能导致突然的渗透压失衡和随后的脱髓鞘综合征。我们描述了一位 65 岁男性,因甲状腺功能亢进症引起的冷漠性脑病,伴有营养不良和严重的硫胺素耗竭。

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Acta Biomed. 2021 Feb 5;92(1):e2021055. doi: 10.23750/abm.v92i1.9473.
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Wernicke Encephalopathy-Clinical Pearls.Wernicke 脑病——临床要点。
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Magnetic resonance imaging in the assessment of brain involvement in alcoholic and nonalcoholic Wernicke's encephalopathy.磁共振成像在评估酒精性和非酒精性韦尼克脑病的脑受累情况中的应用
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Apathetic thyrotoxicosis presenting with diabetes mellitus.以糖尿病为表现的淡漠型甲状腺毒症
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