整合性接合元件介导的多重耐药血清型奥尔巴尼菌株对阿奇霉素的耐药性
Integrative and Conjugative Element-Mediated Azithromycin Resistance in Multidrug-Resistant serovar Albany.
作者信息
Hong Yu-Ping, Chen Ying-Tsong, Wang You-Wun, Chen Bo-Han, Teng Ru-Hsiou, Chen Yi-Syong, Chiou Chien-Shun
机构信息
Centers for Disease Control, Taichung, Taiwan.
National Chung Hsing University, Taichung, Taiwan.
出版信息
Antimicrob Agents Chemother. 2023 May 1;65(5). doi: 10.1128/AAC.02634-20. Epub 2021 Mar 8.
Abstract
We identified an -carrying integrative and conjugative element, ICE_erm42, in 26.4% of multidrug-resistant serovar Albany isolates recovered from human salmonellosis between 2014 and 2019 in Taiwan. ICE_erm42-carrying strains displayed high-level resistance to azithromycin and the element could move into the phylogenetically distant via conjugation.
摘要
我们在2014年至2019年期间从台湾人类沙门氏菌病中分离出的26.4%的多重耐药奥尔巴尼血清型菌株中，鉴定出一种携带erm42的整合和接合元件ICE_erm42。携带ICE_erm42的菌株对阿奇霉素表现出高水平耐药，并且该元件可通过接合转移到系统发育距离较远的菌株中。
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