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约旦圆锥角膜患者的特征:基于医院的人群研究

Characteristics of Keratoconus Patients in Jordan: Hospital-Based Population.

作者信息

Alqudah Noor, Jammal Hisham, Khader Yousef, Al-Dolat Wedad, Alshamarti Sarah, Shannak Zaki

机构信息

Department of Ophthalmology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.

Department of Public Health, Community Medicine and Family Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.

出版信息

Clin Ophthalmol. 2021 Mar 1;15:881-887. doi: 10.2147/OPTH.S298400. eCollection 2021.

Abstract

PURPOSE

To study the demographic, clinical and topographic characteristics of keratoconus patients in Jordan.

METHODS

A retrospective study which was conducted at King Abdullah University Hospital, Northern Jordan. The patients who visited our outpatient clinic from March 2015 to September 2020 and had a definite diagnosis of keratoconus were included in this study. Demographic and clinical data, including age, gender, family history, past ocular history, ophthalmic examination, and topographic parameters, were collected and analysed. Keratoconus severity was classified according to K mean readings.

RESULTS

A total of 234 patients with keratoconus were evaluated in this study. The majority of patients (73, 31.2%) were between the ages of 20 and 24. Allergic conjunctivitis was the most frequent past ocular history. Fifty-five patients (23.5%) had a family history of keratoconus. Regarding severity, most of the eyes were mild (63.3%), followed by moderate (24.7%), and then severe (11.9%). The severity of keratoconus was significantly associated with gender (p<0.001). No correlation was found between family history and severity.

CONCLUSION

Most of the Keratoconus patients were young, with a mean age of 25.9 years. The majority were mild in severity, with more females presented in the severe stage. The study reported high rate of family history (23.5%) in comparison to similar studies. Therefore, screening of family members of Keratoconus patients is advisable.

摘要

目的

研究约旦圆锥角膜患者的人口统计学、临床和地形学特征。

方法

在约旦北部的阿卜杜拉国王大学医院进行一项回顾性研究。纳入2015年3月至2020年9月期间到我们门诊就诊且确诊为圆锥角膜的患者。收集并分析人口统计学和临床数据,包括年龄、性别、家族史、既往眼部病史、眼科检查和地形学参数。根据角膜平均读数对圆锥角膜严重程度进行分类。

结果

本研究共评估了234例圆锥角膜患者。大多数患者(73例,31.2%)年龄在20至24岁之间。过敏性结膜炎是最常见的既往眼部病史。55例患者(23.5%)有圆锥角膜家族史。关于严重程度,大多数眼睛为轻度(63.3%),其次是中度(24.7%),然后是重度(11.9%)。圆锥角膜的严重程度与性别显著相关(p<0.001)。家族史与严重程度之间未发现相关性。

结论

大多数圆锥角膜患者较年轻,平均年龄为25.9岁。大多数病情为轻度,重度阶段女性患者较多。与类似研究相比,本研究报告的家族史发生率较高(23.5%)。因此,建议对圆锥角膜患者的家庭成员进行筛查。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0800/7935342/d82c3e713594/OPTH-15-881-g0001.jpg

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