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巴基斯坦女性乳腺癌需要更好的报告和宣传活动。

Better Reporting and Awareness Campaigns Needed for Breast Cancer in Pakistani Women.

作者信息

Khan Nazeer Hussain, Duan Shao-Feng, Wu Dong-Dong, Ji Xin-Ying

机构信息

Henan International Joint Laboratory for Nuclear Protein Regulation, Henan University, Kaifeng, Henan, 475004, People's Republic of China.

School of Life Sciences, Henan University, Kaifeng, Henan, 475004, People's Republic of China.

出版信息

Cancer Manag Res. 2021 Mar 2;13:2125-2129. doi: 10.2147/CMAR.S270671. eCollection 2021.

DOI:10.2147/CMAR.S270671
PMID:33688255
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7936924/
Abstract

Breast cancer is the most commonly diagnosed cancer and the leading cause of cancer deaths in women globally. In 2018, 2.1 million new cases were reported, with 627,000 deaths. Pakistan has the highest incidence rate of breast cancer among Asian countries: one in every nine women has a lifetime risk of being diagnosed with breast cancer. By reason of many misconceptions about the etiology of the disease and socioeconomic factors, Pakistani women have very low rates of early detection and diagnose breast cancer at advance stages with fewer chances of survival. The key to cure the breast cancer is early diagnosis. The aim of current review is to highlight the factors leading to the delays in early presentation of breast cancer in Pakistani women and to summarize possible recommendations for educating women about early diagnosis along with palliative care facilities for patients suffering from breast cancer. Furthermore, this study appeals to both the general public and government in the belief that better reporting and awareness campaigns may bring more women to clinics for early diagnosis.

摘要

乳腺癌是全球女性中最常被诊断出的癌症,也是癌症死亡的主要原因。2018年,报告了210万新病例,其中62.7万人死亡。在亚洲国家中,巴基斯坦的乳腺癌发病率最高:每九名女性中就有一人一生中患乳腺癌的风险。由于对该疾病病因的诸多误解以及社会经济因素,巴基斯坦女性的早期检测率极低,乳腺癌多在晚期被诊断出来,存活几率较小。治愈乳腺癌的关键是早期诊断。本综述的目的是强调导致巴基斯坦女性乳腺癌早期就诊延迟的因素,并总结对女性进行早期诊断教育的可能建议,以及为乳腺癌患者提供姑息治疗设施。此外,本研究呼吁公众和政府,相信更好的报告和宣传活动可能会让更多女性前往诊所进行早期诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e1a/7936924/f81955d2830a/CMAR-13-2125-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e1a/7936924/f81955d2830a/CMAR-13-2125-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e1a/7936924/f81955d2830a/CMAR-13-2125-g0001.jpg

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JCO Glob Oncol. 2020 Jun;6:873-883. doi: 10.1200/GO.20.00034.
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A multicenter case control study of association of vitamin D with breast cancer among women in Karachi, Pakistan.巴基斯坦卡拉奇地区女性维生素 D 与乳腺癌关联性的多中心病例对照研究。
PLoS One. 2020 Jan 22;15(1):e0225402. doi: 10.1371/journal.pone.0225402. eCollection 2020.
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Spectrum and prevalence of germline mutations in Pakistani breast cancer patients: results from a large comprehensive study.
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PLoS One. 2025 Apr 17;20(4):e0321634. doi: 10.1371/journal.pone.0321634. eCollection 2025.
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Medicine (Baltimore). 2025 Apr 4;104(14):e42076. doi: 10.1097/MD.0000000000042076.
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