• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

用生物陶瓷直接盖髓后修复性牙本质桥形成的评估

Evaluation of Reparative Dentine Bridge Formation after Direct Pulp Capping with Biodentine.

作者信息

Bui Anh Huynh, Pham Khoa Van

机构信息

Department of Operative Dentistry and Endodontics, Faculty of Odonto-Stomatology, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam.

出版信息

J Int Soc Prev Community Dent. 2021 Jan 30;11(1):77-82. doi: 10.4103/jispcd.JISPCD_390_20. eCollection 2021 Jan-Feb.

DOI:10.4103/jispcd.JISPCD_390_20
PMID:33688476
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7934826/
Abstract

AIM

To evaluate the capability of Biodentine for direct pulp capping in permanent teeth.

MATERIALS AND METHODS

The pulp of 11 human intact premolars were mechanically exposed in standard cavity dimensions and then capped with Biodentine for direct pulp capping. After 9-12 weeks, all teeth were extracted. All teeth were scanned using intraoral radiograph or cone-beam computed tomography (CBCT) scan before, right after pulp capping therapy, and after 9-12 weeks on both patient real and extracted teeth for evaluation of reparative dentin bridge formation. All clinical symptoms and signs were also recorded. Data were collected and analyzed using the MedCal statistical software at the significance of 0.05.

RESULTS

There was reparative dentin bridge formation in all experimental teeth, on both patient real and extracted teeth.

CONCLUSIONS

The Biodentine could induce the formation of reparative dentin in direct pulp capping. The CBCT scan was the reliable modality for evaluation of dentin bridge formation.

摘要

目的

评估百康特用于恒牙直接盖髓的能力。

材料与方法

11颗人类完整前磨牙的牙髓经机械暴露,形成标准洞形,然后用百康特进行直接盖髓。9至12周后,拔除所有牙齿。在盖髓治疗前、治疗刚结束时以及9至12周后,对患者的真实牙齿和拔除的牙齿均使用口腔内X光片或锥形束计算机断层扫描(CBCT)进行扫描,以评估修复性牙本质桥的形成情况。同时记录所有临床症状和体征。使用MedCal统计软件收集和分析数据,显著性水平为0.05。

结果

在所有实验牙齿中,无论是患者的真实牙齿还是拔除的牙齿,均有修复性牙本质桥形成。

结论

百康特在直接盖髓中可诱导修复性牙本质的形成。CBCT扫描是评估牙本质桥形成的可靠方式。

相似文献

1
Evaluation of Reparative Dentine Bridge Formation after Direct Pulp Capping with Biodentine.用生物陶瓷直接盖髓后修复性牙本质桥形成的评估
J Int Soc Prev Community Dent. 2021 Jan 30;11(1):77-82. doi: 10.4103/jispcd.JISPCD_390_20. eCollection 2021 Jan-Feb.
2
Tomographic Evaluation of Reparative Dentin Formation after Direct Pulp Capping with Ca(OH)2, MTA, Biodentine, and Dentin Bonding System in Human Teeth.人牙用氢氧化钙、MTA、生物活性玻璃陶瓷和牙本质粘结系统直接盖髓后修复性牙本质形成的断层扫描评估
J Endod. 2015 Aug;41(8):1234-40. doi: 10.1016/j.joen.2015.03.017. Epub 2015 May 29.
3
Dentinogenic responses after direct pulp capping of miniature swine teeth with Biodentine.用生物陶瓷对小型猪牙齿进行直接盖髓后的牙本质生成反应
J Endod. 2014 Dec;40(12):1967-71. doi: 10.1016/j.joen.2014.07.021. Epub 2014 Oct 11.
4
Histological Evaluation of Human Pulp Response to Direct Pulp Capping with MTA, CEM Cement, and Biodentine.人牙髓对MTA、CEM水门汀和生物陶瓷直接盖髓反应的组织学评价
J Dent (Shiraz). 2020 Sep;21(3):177-183. doi: 10.30476/DENTJODS.2019.81796.0.
5
Analysis of hard tissue regeneration and Wnt signalling in dental pulp tissues after direct pulp capping with different materials.不同材料直接盖髓后牙髓组织中硬组织再生和 Wnt 信号转导的分析。
Int Endod J. 2019 Nov;52(11):1605-1616. doi: 10.1111/iej.13162. Epub 2019 Jun 17.
6
Tomographic evaluation of direct pulp capping using a novel injectable treated dentin matrix hydrogel: a 2-year randomized controlled clinical trial.使用新型可注射处理牙本质基质水凝胶进行直接盖髓术的断层扫描评估:一项为期2年的随机对照临床试验。
Clin Oral Investig. 2021 Jul;25(7):4621-4634. doi: 10.1007/s00784-021-03775-1. Epub 2021 Jan 28.
7
Response of human dental pulp capped with biodentine and mineral trioxide aggregate.人牙髓用生物陶瓷和三氧化矿物凝聚体覆盖的反应。
J Endod. 2013 Jun;39(6):743-7. doi: 10.1016/j.joen.2013.01.005. Epub 2013 Apr 10.
8
Histological evaluation of the regenerative potential of a novel treated dentin matrix hydrogel in direct pulp capping.新型处理牙本质基质水凝胶在直接盖髓术中再生潜力的组织学评估。
Clin Oral Investig. 2021 Apr;25(4):2101-2112. doi: 10.1007/s00784-020-03521-z. Epub 2020 Aug 19.
9
Effect of four direct pulp capping agents on human dental pulp tissue.四种直接盖髓剂对人牙髓组织的影响。
Bioinformation. 2024 Jul 31;20(7):785-788. doi: 10.6026/973206300200785. eCollection 2024.
10
Evaluation of reparative dentin formation of ProRoot MTA, Biodentine and BioAggregate using micro-CT and immunohistochemistry.使用微型计算机断层扫描和免疫组织化学评估ProRoot MTA、Biodentine和BioAggregate的修复性牙本质形成情况。
Restor Dent Endod. 2016 Feb;41(1):29-36. doi: 10.5395/rde.2016.41.1.29. Epub 2016 Jan 4.

引用本文的文献

1
Comparative Evaluation of Three Calcium Silicate-Based Materials for Direct Pulp Capping: An Study in Mice.三种硅酸钙基材料用于直接盖髓的比较评价:一项在小鼠中的研究。
bioRxiv. 2025 May 30:2025.05.29.656939. doi: 10.1101/2025.05.29.656939.
2
Outcomes of vital pulp therapy using various pulp capping agents.使用各种盖髓剂进行活髓治疗的结果。
J Conserv Dent Endod. 2025 Feb;28(2):138-143. doi: 10.4103/JCDE.JCDE_817_24. Epub 2025 Feb 3.
3
Calcium Carbonate from Anadara granosa Shells Stimulates FGF2, TGF-β1, and Collagen Type 1 Expression in Rat Dental Pulp.

本文引用的文献

1
Acemannan Used as an Implantable Biomaterial for Vital Pulp Therapy of Immature Permanent Teeth Induced Continued Root Formation.乙酰甘露聚糖用作可植入生物材料用于未成熟恒牙活髓治疗诱导牙根继续发育。
Pharmaceutics. 2020 Jul 8;12(7):644. doi: 10.3390/pharmaceutics12070644.
2
Bio-Inductive Materials in Direct and Indirect Pulp Capping-A Review Article.直接和间接盖髓术中的生物诱导材料——一篇综述文章
Materials (Basel). 2020 Mar 7;13(5):1204. doi: 10.3390/ma13051204.
3
Direct Pulp Capping: Which is the Most Effective Biomaterial? A Retrospective Clinical Study.
来自泥蚶贝壳的碳酸钙刺激大鼠牙髓中FGF2、TGF-β1和I型胶原蛋白的表达。
Eur J Dent. 2025 Jul;19(3):811-816. doi: 10.1055/s-0044-1793842. Epub 2024 Dec 30.
4
The Outcome of GaAlAs Diode Laser (980 Nm) Pulpotomy in Patients with Symptomatic Irreversible Pulpitis Assessed Using CBCT - Randomised Controlled Trial with an 18-Month Follow-up.使用锥形束 CT 评估 GaAlAs 二极管激光(980nm)牙髓切断术治疗症状性不可复性牙髓炎患者的疗效:一项 18 个月随访的随机对照试验。
Eur Endod J. 2024 Jan 1;9(1):35-43. doi: 10.14744/eej.2023.72687.
5
Evaluation of the chemical, physical, and biological properties of a newly developed bioceramic cement derived from cockle shells: an in vitro study.评估一种新型贝壳衍生生物陶瓷水泥的化学、物理和生物学性能:一项体外研究。
BMC Oral Health. 2023 Jun 3;23(1):354. doi: 10.1186/s12903-023-03073-0.
6
An Updated Review on Properties and Indications of Calcium Silicate-Based Cements in Endodontic Therapy.根管治疗中硅酸钙基水门汀的性能与适应证最新综述
Int J Dent. 2022 Oct 30;2022:6858088. doi: 10.1155/2022/6858088. eCollection 2022.
7
The Understanding of Vital Pulp Therapy in Permanent Teeth: A New Perspective.恒牙牙髓治疗的理解:新视角。
Biomed Res Int. 2022 Sep 12;2022:8788358. doi: 10.1155/2022/8788358. eCollection 2022.
8
The Influence of New Bioactive Materials on Pulp-Dentin Complex Regeneration in the Assessment of Cone Bone Computed Tomography (CBCT) and Computed Micro-Tomography (Micro-CT) from a Present and Future Perspective-A Systematic Review.从当前和未来视角评估锥形束计算机断层扫描(CBCT)和计算机显微断层扫描(Micro-CT)中新型生物活性材料对牙髓-牙本质复合体再生的影响——一项系统综述
J Clin Med. 2022 May 30;11(11):3091. doi: 10.3390/jcm11113091.
9
Local Drug Delivery Systems for Vital Pulp Therapy: A New Hope.用于牙髓治疗的局部给药系统:新希望
Int J Biomater. 2021 Sep 15;2021:5584268. doi: 10.1155/2021/5584268. eCollection 2021.
直接盖髓术:哪种生物材料最有效?一项回顾性临床研究。
Materials (Basel). 2019 Oct 16;12(20):3382. doi: 10.3390/ma12203382.
4
How does the pulpal response to Biodentine and ProRoot mineral trioxide aggregate compare in the laboratory and clinic?在实验室和临床中,牙髓对生物陶瓷和MTA(ProRoot矿物三氧化物凝聚体)的反应有何比较?
Br Dent J. 2018 Oct 19. doi: 10.1038/sj.bdj.2018.864.
5
Biodentine versus mineral trioxide aggregate as a direct pulp capping material for human mature permanent teeth - A systematic review.生物活性玻璃陶瓷与三氧化矿物凝聚体作为人类成熟恒牙直接盖髓材料的系统评价
J Conserv Dent. 2018 Sep-Oct;21(5):466-473. doi: 10.4103/JCD.JCD_198_18.
6
Outcomes of Direct Pulp Capping by Using Either ProRoot Mineral Trioxide Aggregate or Biodentine in Permanent Teeth with Carious Pulp Exposure in 6- to 18-Year-Old Patients: A Randomized Controlled Trial.在 6 至 18 岁患有牙髓暴露性龋损的恒牙中,使用 ProRoot 矿化三氧化物凝聚体或 Biodentine 直接盖髓的疗效比较:一项随机对照试验。
J Endod. 2018 Mar;44(3):341-348. doi: 10.1016/j.joen.2017.10.012. Epub 2017 Dec 21.
7
Direct Pulp Capping with Calcium Hydroxide, Mineral Trioxide Aggregate, and Biodentine in Permanent Young Teeth with Caries: A Randomized Clinical Trial.直接盖髓术用氢氧化钙、三氧化矿物凝聚体和生物陶瓷在有龋的年轻恒牙中的应用:一项随机临床试验。
J Endod. 2017 Nov;43(11):1776-1780. doi: 10.1016/j.joen.2017.06.031. Epub 2017 Sep 14.
8
Clinical evaluation of mineral trioxide aggregate and biodentine as direct pulp capping agents in carious teeth.矿物三氧化物凝聚体和生物陶瓷作为龋病牙齿直接盖髓剂的临床评价
J Conserv Dent. 2017 Mar-Apr;20(2):91-95. doi: 10.4103/0972-0707.212243.
9
Human Pulp Responses to Partial Pulpotomy Treatment with TheraCal as Compared with Biodentine and ProRoot MTA: A Clinical Trial.TheraCal 与 Biodentine 和 ProRoot MTA 行部分活髓切断术治疗的人牙髓反应:一项临床试验。
J Endod. 2017 Nov;43(11):1786-1791. doi: 10.1016/j.joen.2017.06.025. Epub 2017 Aug 16.
10
Evaluation of indirect pulp capping using three different materials: A randomized control trial using cone-beam computed tomography.使用三种不同材料进行间接盖髓术的评估:一项使用锥形束计算机断层扫描的随机对照试验。
Indian J Dent Res. 2016 Nov-Dec;27(6):623-629. doi: 10.4103/0970-9290.199588.