Division of Anesthesia and Intensive Care, Department of Human Pathology of the Adult and Evolutive Age "Gaetano Barresi", University of Messina, Policlinico "G. Martino", Via Consolare Valeria, 1, 98100, Messina, Italy.
IPCF-CNR, Institute for Chemical and Physical Processes, National Research Council, Messina, Italy.
Sci Rep. 2021 Mar 10;11(1):5559. doi: 10.1038/s41598-021-85093-w.
During the COVID-19 pandemic, the need for noninvasive respiratory support devices has dramatically increased, sometimes exceeding hospital capacity. The full-face Decathlon snorkeling mask, EasyBreath (EB mask), has been adapted to deliver continuous positive airway pressure (CPAP) as an emergency respiratory interface. We aimed to assess the performance of this modified EB mask and to test its use during different gas mixture supplies. CPAP set at 5, 10, and 15 cmHO was delivered to 10 healthy volunteers with a high-flow system generator set at 40, 80, and 120 L min and with a turbine-driven ventilator during both spontaneous and loaded (resistor) breathing. Inspiratory CO partial pressure (PiCO), pressure inside the mask, breathing pattern and electrical activity of the diaphragm (EAdi) were measured at all combinations of CPAP/flows delivered, with and without the resistor. Using the high-flow generator set at 40 L min, the PiCO significantly increased and the system was unable to maintain the target CPAP of 10 and 15 cmHO and a stable pressure within the respiratory cycle; conversely, the turbine-driven ventilator did. EAdi significantly increased with flow rates of 40 and 80 L min but not at 120 L min and with the turbine-driven ventilator. EB mask can be safely used to deliver CPAP only under strict constraints, using either a high-flow generator at a flow rate greater than 80 L min, or a high-performance turbine-driven ventilator.
在 COVID-19 大流行期间,对非侵入性呼吸支持设备的需求急剧增加,有时甚至超过了医院的容量。全脸十项全能潜水呼吸管面罩(EasyBreath,EB 面罩)已被改装为提供持续气道正压通气(CPAP)的紧急呼吸接口。我们旨在评估这种改良的 EB 面罩的性能,并测试其在不同气体混合物供应下的使用情况。使用高流量系统在 40、80 和 120 L/min 的流速下向 10 名健康志愿者输送 CPAP 设置为 5、10 和 15 cmHO,并用涡轮驱动呼吸机在自主呼吸和负载(电阻器)呼吸下进行。在所有 CPAP/流速组合下测量吸气 CO 分压(PiCO)、面罩内压力、呼吸模式和膈肌电活动(EAdi),并在有和没有电阻器的情况下进行。使用高流量发生器设置为 40 L/min 时,PiCO 显著增加,系统无法维持 10 和 15 cmHO 的目标 CPAP 以及呼吸周期内的稳定压力;相反,涡轮驱动呼吸机可以。EAdi 在流速为 40 和 80 L/min 时显著增加,但在 120 L/min 时和使用涡轮驱动呼吸机时没有增加。只有在严格限制下,EB 面罩才能安全地用于输送 CPAP,方法是使用高流量发生器以大于 80 L/min 的流速,或使用高性能涡轮驱动呼吸机。