Chang Kai-Ming, Hsieh Sharon L, Koshy Robin
Division of Infectious Diseases, Department of Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell Health, Manhasset, USA.
Internal Medicine, University of Miami Leonard M. Miller School of Medicine, Miami, FL, USA.
Cureus. 2021 Feb 6;13(2):e13171. doi: 10.7759/cureus.13171.
group (SAG) is a subgroup of viridans streptococci and can be found ubiquitously in normal human flora. SAG is known to form invasive pyogenic infection when it becomes pathogenic. Yet, SAG is a very rare cause of endocarditis, and there is a dearth of case reports on this topic. We present a rare case of native bicuspid aortic valve endocarditis secondary to that caused aortic insufficiency and ascending aortic aneurysm. To our knowledge, this is the first well-documented case report of community-acquired endocarditis on a bicuspid aortic valve in an immunocompetent patient. The patient first presented with cough that was likely due to bronchus irritation from a 5.5 x 5.2 cm ascending aortic aneurysm. He underwent aortic valve replacement with bovine bioprosthesis and ascending aortic aneurysm repairment and was treated with a two-week regimen of IV ceftriaxone and gentamicin followed by another four weeks of IV ceftriaxone. He was eventually discharged to a rehabilitation facility. SAG is usually susceptible to beta-lactam antibiotics. The prognosis of SAG infection is usually good, but progression to bacteremia carries a poor outcome.
草绿色链球菌群(SAG)是甲型溶血性链球菌的一个亚群,在正常人体菌群中普遍存在。已知SAG致病时会形成侵袭性化脓性感染。然而,SAG是心内膜炎非常罕见的病因,关于这一主题的病例报告很少。我们报告一例罕见的原发性二尖瓣主动脉瓣心内膜炎病例,其继发于[此处原文缺失相关病因],导致主动脉瓣关闭不全和升主动脉瘤。据我们所知,这是首例有充分记录的免疫功能正常患者社区获得性二尖瓣主动脉瓣心内膜炎病例。患者最初表现为咳嗽,可能是由于5.5×5.2 cm升主动脉瘤刺激支气管所致。他接受了牛生物瓣膜主动脉瓣置换术和升主动脉瘤修复术,并接受了为期两周的静脉注射头孢曲松和庆大霉素治疗,随后又接受了四周的静脉注射头孢曲松治疗。他最终出院前往康复机构。SAG通常对β-内酰胺类抗生素敏感。SAG感染的预后通常良好,但进展为菌血症则预后不良。