Jelicic Ivo
Renal Unit, University Hospital Split, Split, Croatia.
Hemodial Int. 2021 Jul;25(3):333-337. doi: 10.1111/hdi.12923. Epub 2021 Mar 10.
Intradialytic hypotension is the most common complication during hemodialysis and is associated with increased cardiovascular disease, mortality, and overall hospital admissions. We analyzed the influence of food intake during hemodialysis on intradialytic hypotension.
A total of 105 patients treated with chronic hemodialysis were observed for 8 weeks-4 weeks with a meal during hemodialysis and 4 weeks without a meal.
A statistically significant decrease of hypotensive events (p < 0.001) and cramping episodes (p = 0.035) was observed during a 4-week period without a meal. Patients who were particularly susceptible to intradialytic hypotension were those who were diabetic, had low urinary excretion, and were treated with hemodialysis for a long time. On a follow up, there was a significant increase in serum albumin after 3 months (p = 0.01) and 6 months (p = 0.036) despite meal withdrawal during hemodialysis.
Fasting during hemodialysis may cause a significantly lower frequency of intradialytic hypotension and cramping episodes without affecting the nutritional status.
透析中低血压是血液透析期间最常见的并发症，与心血管疾病、死亡率及总体住院率增加相关。我们分析了血液透析期间进食对透析中低血压的影响。
共观察了105例接受慢性血液透析治疗的患者，为期8周，其中4周在血液透析期间进食，4周在血液透析期间不进食。
在4周不进食期间，低血压事件（p < 0.001）和痉挛发作（p = 0.035）在统计学上显著减少。特别容易发生透析中低血压的患者是糖尿病患者、低尿排泄患者以及长期接受血液透析治疗的患者。随访发现，尽管血液透析期间停止进食，但3个月（p = 0.01）和6个月（p = 0.036）后血清白蛋白显著增加。
血液透析期间禁食可能会使透析中低血压和痉挛发作的频率显著降低，而不影响营养状况。
