Darvell F J, Rossi I R, Rossi M B, Fayers P, Anderson R H, Rigby M L, Shinebourne E A, Lincoln C
Department of Paediatrics, Brompton Hospital, Cardiothoracic Institute, London.
Br Heart J. 1988 Apr;59(4):468-73. doi: 10.1136/hrt.59.4.468.
Overall survival after Mustard's operation was assessed in 130 patients with complete transposition of the great arteries and an intact ventricular septum who were operated on at the Brompton Hospital in the 12 year period from January 1974 to December 1985. Actuarial analysis showed a survival at five years of 79.1% (25 deaths in 130 patients). Half the deaths occurred within a month of operation and half up to five years later. Operation under the age of three months carried a greater mortality (six deaths in 11 patients). Statistical analysis showed that these survival figures were consistent throughout the series and did not alter with the year of operation. In the light of recent trends in treatment of this lesion, it is concluded that for neonates an arterial switch procedure is now likely to carry the best chance of long term success. For the patient who presents after the age of three months, however, there may still be a place for the Mustard procedure.
对1974年1月至1985年12月期间在布朗普顿医院接受手术的130例大动脉完全转位且室间隔完整的患者进行了Mustard手术后的总生存率评估。精算分析显示,五年生存率为79.1%(130例患者中有25例死亡)。一半的死亡发生在术后一个月内,另一半发生在术后五年内。三个月以下婴儿手术的死亡率更高(11例患者中有6例死亡)。统计分析表明,整个系列的这些生存数据是一致的,且不随手术年份而改变。鉴于该病变治疗的最新趋势,得出结论:对于新生儿,动脉调转术现在可能是长期成功的最佳机会。然而,对于三个月以上就诊的患者,Mustard手术可能仍有一席之地。