C.S. Mott Children's Hospital Section of Pediatric Surgery, 1540 East Hospital Drive, Ann Arbor, MI 48109, USA.
University of Michigan, C.S. Mott Children's Hospital Section of Pediatric Surgery, 1540 East Hospital Drive, SPC 4811, Ann Arbor, MI 48109, USA.
Surg Oncol Clin N Am. 2021 Apr;30(2):305-323. doi: 10.1016/j.soc.2020.11.002. Epub 2021 Jan 29.
This article reviews the epidemiology, pathophysiology, clinical presentation, and multimodality management of Wilms tumors and renal cell carcinoma in pediatric and young adults. Key renal Société Internationale d'Oncologie Pédiatrique and Children Oncology Group studies are presented. The article reviews the common staging systems and risk-adapted treatment strategies with particular attention to the surgical management.
本文回顾了小儿和青年人群中肾母细胞瘤和肾细胞癌的流行病学、病理生理学、临床表现和多模态管理。介绍了主要的儿科国际肿瘤学会和儿童肿瘤学组研究。本文还回顾了常见的分期系统和风险适应治疗策略，并特别关注手术管理。
