Moradian Seyed Tayeb, Parandeh Akram, Khalili Robabe, Karimi Leila
Atherosclerosis Research Center, Faculty of Nursing, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Medicine, Quran and Hadith Research Center, Faculty of Nursing, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Iran J Public Health. 2020 Nov;49(11):2120-2127. doi: 10.18502/ijph.v49i11.4729.
COVID-19 is a new disease, so we don't know what comes next. Since information on delayed symptoms is limited, this study was conducted to assess the frequency of delayed symptoms in patients with COVID-19.
This follow-up cross-sectional study was conducted in a referral general hospital in Tehran, Iran from Feb to Apr 2020. Two hundred patients hospitalized for COVID-19 and were discharged were assessed for delayed symptoms 6 wk after discharge.
The mean age of the participants was 55.58±13.52, and 160 (80%) Of them were male. On admission to hospital, patients reported a mean of 5.63±2.88 symptoms per patient, range from 1 to 14 symptoms. Dyspnea was seen in 119 (59.5%) 0f them as the most frequent symptom. Then weakness, myalgia, and shivering were reported with a frequency of 111 (55.5%), 107 (53.5%), and 103 (51.5%), respectively. Six weeks after discharge reassessment was done. None of the patients was readmitted to the hospital. Ninety-four (42%) of them were symptom-free. Fatigue was the most frequent delayed symptom with a frequency of 39 (19.5%), and then dyspnea, weakness, and activity intolerance with a frequency of 37 (18.5%), 36 (18%), and 29 (14.5%) were reported, respectively.
Fatigue, dyspnea, weakness, anxiety, and activity intolerance were most frequent delayed symptoms, respectively. Majority of patient was symptoms free and those with symptom, had mild to moderate symptoms. The importance of symptoms is not fully recognized. Follow up clinics and in some cases rehabilitation programs may be helpful.
2019冠状病毒病是一种新出现的疾病，所以我们不知道接下来会发生什么。由于关于延迟出现症状的信息有限，开展本研究以评估2019冠状病毒病患者延迟出现症状的频率。
本随访横断面研究于2020年2月至4月在伊朗德黑兰一家转诊综合医院进行。对200例因2019冠状病毒病住院且已出院的患者在出院6周后评估其延迟出现的症状。
参与者的平均年龄为55.58±13.52岁，其中160例（80%）为男性。入院时，患者报告的平均症状数为每人5.63±2.88个，范围为1至14个症状。其中119例（59.5%）出现呼吸困难，为最常见症状。然后分别有111例（55.5%）、107例（53.5%）和103例（51.5%）报告有虚弱、肌痛和寒战。出院6周后进行重新评估。无患者再次入院。其中94例（42%）无症状。疲劳是最常见的延迟症状，发生率为39例（19.5%），然后分别有37例（18.5%）、36例（18%）和29例（14.5%）报告有呼吸困难、虚弱和活动不耐受。
疲劳、呼吸困难、虚弱、焦虑和活动不耐受分别是最常见的延迟症状。大多数患者无症状，有症状的患者症状为轻至中度。症状的重要性尚未得到充分认识。随访门诊以及在某些情况下康复计划可能会有帮助。
