Department of Obstetrics and Gynecology, Vittore Buzzi Children's Hospital, University of Milan, Milan, Italy.
Pathology Unit, Department of Biomedical and Clinical Sciences "Luigi Sacco", University of Milan, Milan, Italy.
Reprod Sci. 2021 May;28(5):1277-1280. doi: 10.1007/s43032-021-00463-z. Epub 2021 Mar 11.
The role of a healthy placenta as the interface between mother and fetus, which regulates the intrauterine environment and affects fetal and pregnancy outcomes, points to placental examination as a potentially useful diagnostic tool. Placental macroscopic and microscopic patterns are routinely evaluated when pregnancy complications occur. Moreover, placental measures particularly the ratio between fetal and placental weight have been reported to correlate with maternal characteristics, such as BMI as well as with birth-weight and fetal gender. Our pilot study evaluates the feasibility of the placental measures' reproducibility intra-operators. We enrolled 50 consecutive singleton pregnancies including physiological pregnancies and any pre-existing maternal disease or maternal and fetal complication. We conducted a macroscopic analysis of fetal adnexa with four different operators assessing pathological findings or other abnormalities. Intra-class correlation coefficient (ICC) and Cohen and Fleiss kappa coefficient were used to assess the degree of consistency between operators. The results of our study show that the placental morphometric analysis is a reproducible method.
胎盘作为母体与胎儿之间的界面，调节宫内环境并影响胎儿和妊娠结局，这表明胎盘检查是一种潜在有用的诊断工具。当发生妊娠并发症时，通常会对胎盘的宏观和微观模式进行评估。此外，据报道，胎盘的测量值，特别是胎儿与胎盘重量的比值，与母体特征（如 BMI）以及出生体重和胎儿性别相关。我们的初步研究评估了胎盘测量值在操作者之间的可重复性。我们纳入了 50 例连续的单胎妊娠，包括生理妊娠以及任何先前存在的母体疾病或母体和胎儿并发症。我们由四名不同的操作者进行了胎儿附属物的宏观分析，评估病理发现或其他异常。采用组内相关系数（ICC）和 Cohen 和 Fleiss kappa 系数评估操作者之间的一致性程度。我们的研究结果表明，胎盘形态计量分析是一种可重复的方法。
