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COVID-19 封锁对老年人髋部骨折流行病学的影响:一项多中心队列研究。

The effect of the COVID-19 lockdown on the epidemiology of hip fractures in the elderly: a multicentre cohort study.

机构信息

East Sussex Healthcare NHS Trust, UK.

East Kent Hospitals University NHS Foundation Trust, UK.

出版信息

Ann R Coll Surg Engl. 2021 May;103(5):337-344. doi: 10.1308/rcsann.2020.7071. Epub 2021 Mar 10.

DOI:10.1308/rcsann.2020.7071
PMID:33715420
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10334881/
Abstract

INTRODUCTION

The COVID-19 pandemic presented extraordinary challenges to the UK healthcare system. This study aimed to assess the impact of the COVID-19 lockdown on the epidemiology, treatment pathways and 30-day mortality rates of hip fractures. Outcomes of COVID-19 positive patients were compared against those who tested negative.

METHODS

An observational, retrospective, multicentre study was conducted across six hospitals in the South East of England. Data were retrieved from the National Hip Fracture Database and electronic medical records. Data was collected for the strictest UK lockdown period (period B=23 March 2020-11 May 2020), and the corresponding period in 2019 (period A).

RESULTS

A total of 386 patients were admitted during period A, whereas 381 were admitted during period B. Despite the suspension of the 'Best Practice Tariff' during period B, time to surgery, time to orthogeriatric assessment, and 30-day mortality were similar between period A and B. The length of inpatient stay was significantly shorter during period B (11.5 days vs 17.0 days, <0.001). Comparison of COVID-19 positive and negative patients during period B demonstrated that a positive test was associated with a significantly higher rate of 30-day mortality (53.6% vs 6.7%), surgical delay >36h (46.4% vs 30.8%, =0.049), and increased length of inpatient stay (15.8 vs 11.7 days, =0.015).

CONCLUSIONS

The COVID-19 lockdown did not alter the epidemiology of hip fractures. A substantially higher mortality rate was observed among patients with a COVID-19 positive test. These findings should be taken into consideration by the healthcare policymakers while formulating contingency plans for a potential 'second wave'.

摘要

介绍

COVID-19 大流行给英国医疗保健系统带来了前所未有的挑战。本研究旨在评估 COVID-19 封锁对髋部骨折的流行病学、治疗途径和 30 天死亡率的影响。将 COVID-19 阳性患者的结果与阴性患者进行比较。

方法

在英格兰东南部的六家医院进行了一项观察性、回顾性、多中心研究。从国家髋部骨折数据库和电子病历中检索数据。数据收集了英国最严格的封锁期(期 B=2020 年 3 月 23 日至 2020 年 5 月 11 日)和 2019 年同期(期 A)的数据。

结果

期 A 共收治 386 例患者,期 B 共收治 381 例患者。尽管期 B 暂停了“最佳实践关税”,但手术时间、骨科评估时间和 30 天死亡率在期 A 和 B 之间相似。期 B 的住院时间明显缩短(11.5 天比 17.0 天,<0.001)。期 B 期间 COVID-19 阳性和阴性患者的比较表明,阳性检测与 30 天死亡率显著升高(53.6%比 6.7%,<0.001)、手术延迟>36 小时(46.4%比 30.8%,=0.049)和住院时间延长(15.8 天比 11.7 天,=0.015)相关。

结论

COVID-19 封锁并没有改变髋部骨折的流行病学。COVID-19 阳性检测患者的死亡率显著升高。在制定潜在“第二波”应急计划时,医疗保健政策制定者应考虑到这些发现。

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