Department of Exercise Physiology, University of Isfahan, Isfahan, Iran.
Department of Physical Education & Sport Sciences, Tarbiat Modares University, Tehran, Iran.
Br J Nutr. 2022 Jan 28;127(2):248-256. doi: 10.1017/S000711452100091X. Epub 2021 Mar 15.
We aimed to assess the effects of spirulina supplementation during gradual weight loss on serum concentrations of follistatin (FST), myostatin (MST), insulin-like growth factor 1 (IGF-1), aspartate aminotransferase (AST), alanine aminotransferase (ALT) and body composition in competitive wrestlers. Forty competitive wrestlers (age: 22 (sem 2) years) were randomly assigned to one of two groups: gradual weight loss + spirulina (SP; n 20) or gradual weight loss + placebo (PL; n 20). Subjects in both groups lost weight according to a designed diet over 12 d and were required to reduce baseline body mass (BM) by 4%. Subjects in the SP group received two tablets of spirulina, while subjects in the PL received two tablets of placebo before each meal. Concentrations of mentioned serum markers and body composition were measured before and after the interventions. BM (SP = -3·1 kg and PL = -2·9 kg), body fat percentage (BFP) (SP = -2·1 % and PL = -0·6 %), fat mass (FM) (SP = -2·2 kg and PL = -0·9 kg) and skeletal muscle mass (SP = -1·4 kg and PL = -1·5 kg) significantly decreased in both groups (P < 0·05). The changes in BFP and FM were significantly greater in SP compared with the PL group (P < 0·001). Additionally, MST (SP = -0·1 ng/ml), AST (SP = -2·1 u/l) and ALT (SP = -2·7 u/l) concentrations significantly diminished in SP group (P = 0·005), while FST (PL = -0·1 ng/ml) and IGF-1 (PL = -2·6 ng/ml) concentrations significantly decreased in PL group (P < 0·05). Spirulina supplementation during gradual weight loss is beneficial in reducing BFP, FM, MST and liver enzymes while maintaining IGF-1 and FST concentrations in competitive wrestlers.
我们旨在评估在逐渐减肥过程中补充螺旋藻对竞技摔跤运动员血清中卵泡抑素（FST）、肌肉生长抑制素（MST）、胰岛素样生长因子 1（IGF-1）、天门冬氨酸氨基转移酶（AST）、丙氨酸氨基转移酶（ALT）浓度和身体成分的影响。将 40 名竞技摔跤运动员（年龄：22（标准差 2）岁）随机分为两组：逐渐减肥+螺旋藻（SP；n=20）或逐渐减肥+安慰剂（PL；n=20）。两组受试者均按照设计的饮食在 12 天内减轻体重，要求将基础体重（BM）降低 4%。SP 组受试者每餐服用两片螺旋藻，PL 组受试者每餐服用两片安慰剂。干预前后测量了上述血清标志物和身体成分的浓度。BM（SP=-3.1kg，PL=-2.9kg）、体脂百分比（BFP）（SP=-2.1%，PL=-0.6%）、脂肪量（FM）（SP=-2.2kg，PL=-0.9kg）和骨骼肌量（SP=-1.4kg，PL=-1.5kg）在两组中均显著下降（P<0.05）。与 PL 组相比，SP 组的 BFP 和 FM 变化明显更大（P<0.001）。此外，SP 组 MST（SP=-0.1ng/ml）、AST（SP=-2.1u/l）和 ALT（SP=-2.7u/l）浓度显著降低（P=0.005），而 PL 组 FST（PL=-0.1ng/ml）和 IGF-1（PL=-2.6ng/ml）浓度显著降低（P<0.05）。在逐渐减肥过程中补充螺旋藻有助于降低竞技摔跤运动员的 BFP、FM、MST 和肝酶，同时维持 IGF-1 和 FST 浓度。
