Singh Romil, Shaik Likhita, Mehra Ishita, Kashyap Rahul, Surani Salim
Department of Medicine, Metropolitan Hospital, Jaipur, Rajasthan, India.
Department of Oncology, Department of Medicine, Mayo Clinic, Rochester, MN, USA.
Open Respir Med J. 2020 Dec 31;14:79-86. doi: 10.2174/1874306402014010079. eCollection 2020.
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the coronavirus disease (COVID-19) pandemic, which has led scientists all over the world to push for the identification of novel therapies for COVID-19. The lack of a vaccine and specific treatment has led to a surge of novel therapies and their publicity in recent times. Under these unprecedented circumstances, a myriad of drugs used for other diseases is being evaluated and repositioned to treat COVID-19 (example- Remdesivir, Baricitinib). While multiple trials for potential drugs and vaccines are ongoing, and there are many unproven remedies with little or no supporting evidence. Presently, discussions are revolving around the use of multivitamins (Vitamin, C, D, A), minerals (selenium, zinc), probiotics, flavonoids, polyphenols, and herbal remedies (curcumin, artemisinin, herbal drinks). Our review delves further into the details of some of these controversial therapies for COVID-19.
严重急性呼吸综合征冠状病毒2（SARS-CoV-2）引发了冠状病毒病（COVID-19）大流行，这促使世界各地的科学家努力寻找针对COVID-19的新型疗法。由于缺乏疫苗和特效治疗方法，近期新型疗法及其宣传激增。在这些前所未有的情况下，多种用于其他疾病的药物正在接受评估并被重新定位用于治疗COVID-19（例如瑞德西韦、巴瑞替尼）。虽然针对潜在药物和疫苗的多项试验正在进行，但也有许多未经证实的疗法，几乎没有或根本没有支持证据。目前，讨论主要围绕多种维生素（维生素C、D、A）、矿物质（硒、锌）、益生菌、类黄酮、多酚和草药疗法（姜黄素、青蒿素、草药饮品）的使用展开。我们的综述将进一步深入探讨其中一些针对COVID-19的有争议疗法的细节。
