Li Xianhui, Tan Sheng, Luo Jianquan, Pinelo Manuel
Process and Systems Engineering Center (PROSYS), Department of Chemical and Biochemical Engineering, Technical University of Denmark, DK-2800 Lyngby, Denmark.
State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing, 100190 China.
Front Chem Sci Eng. 2021;15(4):837-853. doi: 10.1007/s11705-020-2020-z. Epub 2021 Mar 8.
Saccharide production is critical to the development of biotechnology in the field of food and biofuel. The extraction of saccharide from biomass-based hydrolysate mixtures has become a trend due to low cost and abundant biomass reserves. Compared to conventional methods of fractionation and recovery of saccharides, nanofiltration (NF) has received considerable attention in recent decades because of its high selectivity and low energy consumption and environmental impact. In this review the advantages and challenges of NF based technology in the separation of saccharides are critically evaluated. Hybrid membrane processes, i.e., combining NF with ultrafiltration, can complement each other to provide an efficient approach for removal of unwanted solutes to obtain higher purity saccharides. However, use of NF membrane separation technology is limited due to irreversible membrane fouling that results in high capital and operating costs. Future development of NF membrane technology should therefore focus on improving material stability, antifouling ability and saccharide targeting selectivity, as well as on engineering aspects such as process optimisation and membrane module design.
糖类生产对于食品和生物燃料领域的生物技术发展至关重要。从基于生物质的水解产物混合物中提取糖类，由于成本低且生物质储量丰富，已成为一种趋势。与传统的糖类分馏和回收方法相比，近几十年来，纳滤（NF）因其高选择性、低能耗和对环境影响小而备受关注。在这篇综述中，对基于纳滤技术在糖类分离中的优势和挑战进行了批判性评估。混合膜工艺，即将纳滤与超滤相结合，可以优势互补，为去除不需要的溶质以获得更高纯度的糖类提供一种有效方法。然而，由于不可逆的膜污染导致高昂的资本和运营成本，纳滤膜分离技术的应用受到限制。因此，纳滤膜技术的未来发展应侧重于提高材料稳定性、抗污染能力和糖类靶向选择性，以及诸如工艺优化和膜组件设计等工程方面。
