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低温等离子体在制药领域的应用与挑战

Applications and challenges of low temperature plasma in pharmaceutical field.

作者信息

Gao Lingge, Shi Xingmin, Wu Xili

机构信息

School of Public Health, Medical Science Center, Xi'an Jiaotong University, Xi'an, 710061, China.

Second Affiliated Hospital, Xi'an Jiaotong University, Xi'an, 710004, China.

出版信息

J Pharm Anal. 2021 Feb;11(1):28-36. doi: 10.1016/j.jpha.2020.05.001. Epub 2020 May 11.

DOI:10.1016/j.jpha.2020.05.001
PMID:33717609
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7930796/
Abstract

Low temperature plasma (LTP) technology has shown an outstanding application value in the pharmaceutical filed in recent ten years. This paper reviews the research advances in LTP, including its effects on enhancing or inhibiting drug activity, its combined use with drugs to treat cancers, its effects on the improvement of drug delivery system, its use in preparation of new inactivated virus vaccines, its use with mass spectrometry for rapid detection of drug quality, and the anti-tumor and sterilization effects of plasma-activated liquids. The paper also analyzes the challenges of LTP in the pharmaceutical filed, hoping to promote related research.

摘要

近十年来，低温等离子体（LTP）技术在制药领域展现出了卓越的应用价值。本文综述了LTP的研究进展，包括其对药物活性的增强或抑制作用、与药物联合用于治疗癌症、对药物递送系统改善的作用、在新型灭活病毒疫苗制备中的应用、与质谱联用用于药物质量的快速检测，以及等离子体激活液体的抗肿瘤和杀菌作用。本文还分析了LTP在制药领域面临的挑战，希望推动相关研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fb4/7930796/f74311545f9a/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fb4/7930796/fadbd1b4ddfe/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fb4/7930796/92d5b1856991/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fb4/7930796/501eba9ae8e2/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fb4/7930796/201278f9cc36/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fb4/7930796/0d2062f44f41/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fb4/7930796/f74311545f9a/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fb4/7930796/fadbd1b4ddfe/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fb4/7930796/92d5b1856991/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fb4/7930796/501eba9ae8e2/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fb4/7930796/201278f9cc36/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fb4/7930796/0d2062f44f41/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fb4/7930796/f74311545f9a/gr5.jpg

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