Division of thyroid Surgery, China-Japan Union Hospital Of Jilin University, Jilin Provincial Key Laboratory Of Surgical Translational Medicine, Jilin Provincial Precision Medicine Laboratory of Molecular Biology and Translational Medicine on Differentiated Thyroid Carcinoma, 126 Xiantai Blvd, Changchun City, Jilin Province, People's Republic of China.
Division for Endocrine and Minimally Invasive Surgery, Department of Human Pathology in Adulthood and Childhood "G. Barresi", University Hospital G. Martino, University of Messina, Via C. Valeria 1, 98125, Messina, Italy.
Langenbecks Arch Surg. 2021 Dec;406(8):2869-2877. doi: 10.1007/s00423-021-02124-w. Epub 2021 Mar 15.
The transoral endoscopic thyroidectomy vestibular approach (TOETVA) has emerged as a new treatment option for patients with selected thyroid disease requiring surgery. The aim of this pictorial essay is to illustrate the healing outcomes of the vestibular incisions.
TOETVA patients were recruited at two Centers in China and Italy. TOETVA is initiated with one 10-20-mm median incision in the center of the oral vestibule 10 mm above the inferior labial frenulum, and two 5-mm lateral incisions, just below the lower lip near the labial commissure. Healing of the vestibular incision was monitored through serial photographs 1, 3, 7, 30, and 90 days after surgery. Outcomes were evaluated by Landry's score, time to healing, issues affecting wound outcomes, scar, fibrin, granulation, necrotic tissue formation, and infections.
Results of TOETVA were monitored in 52 patients. There were no postoperative infections. All lateral incisions demonstrated favorable surgical outcomes. Landry's criteria scores indicated worse outcomes for the median incisions vs. the lateral ones (p<0.05). Median incisions healed well in 65.4% of patients, but 34.6% of patients had visible scars from the median incision 90 days after surgery. Eight (15.4%) had cicatricial diathesis, seven (13.5%) experienced displacement of the stitches, and three (5.8%) developed synechia with gingiva. When the central vestibular incision was <10mm from the gingiva, patients tended to form synechia (60%). There were no significant differences in wound healing between the Chinese and Italian patients.
Knowledge of vestibular incision healing is essential to provide practical TOETVA clinical guide and to define optimal outcomes evaluation for transoral surgeons. Vestibular wound problems were confined only to the central incision.
经口内镜甲状腺切除术前庭入路(TOETVA)已成为一种新的治疗选择,适用于需要手术治疗的特定甲状腺疾病患者。本文旨在阐述前庭切口的愈合结果。
在中国和意大利的两个中心招募 TOETVA 患者。TOETVA 手术始于口腔前庭正中 10mm 处的 10-20mm 中切口,位于下唇下切迹上方 10mm 处,以及下唇附近唇联合处的两个 5mm 侧切口。术后 1、3、7、30 和 90 天通过连续照片监测前庭切口的愈合情况。采用 Landry 评分、愈合时间、影响伤口愈合的问题、瘢痕、纤维蛋白、肉芽组织、坏死组织形成和感染等来评估结果。
共监测了 52 例 TOETVA 结果。无术后感染。所有侧切口均获得良好的手术效果。Landry 标准评分表明,与侧切口相比,中切口的结果更差(p<0.05)。65.4%的患者中切口愈合良好,但 34.6%的患者术后 90 天仍可见中切口瘢痕。8 例(15.4%)有瘢痕体质,7 例(13.5%)缝线移位,3 例(5.8%)与牙龈发生粘连。当中央前庭切口距离牙龈<10mm 时,患者容易发生粘连(60%)。中国和意大利患者的伤口愈合无显著差异。
了解前庭切口愈合情况对于提供实用的 TOETVA 临床指导和定义经口外科医生的最佳结局评估至关重要。仅中央切口出现伤口愈合问题。