IEEE Trans Med Imaging. 2021 Jul;40(7):1763-1777. doi: 10.1109/TMI.2021.3065918. Epub 2021 Jun 30.
Automated segmentation of brain glioma plays an active role in diagnosis decision, progression monitoring and surgery planning. Based on deep neural networks, previous studies have shown promising technologies for brain glioma segmentation. However, these approaches lack powerful strategies to incorporate contextual information of tumor cells and their surrounding, which has been proven as a fundamental cue to deal with local ambiguity. In this work, we propose a novel approach named Context-Aware Network (CANet) for brain glioma segmentation. CANet captures high dimensional and discriminative features with contexts from both the convolutional space and feature interaction graphs. We further propose context guided attentive conditional random fields which can selectively aggregate features. We evaluate our method using publicly accessible brain glioma segmentation datasets BRATS2017, BRATS2018 and BRATS2019. The experimental results show that the proposed algorithm has better or competitive performance against several State-of-The-Art approaches under different segmentation metrics on the training and validation sets.
脑胶质瘤的自动分割在诊断决策、进展监测和手术规划中起着积极的作用。基于深度学习网络,已有研究表明,该技术在脑胶质瘤分割方面具有广阔的应用前景。然而,这些方法缺乏强大的策略来整合肿瘤细胞及其周围环境的上下文信息,而上下文信息已被证明是解决局部歧义的基本线索。在这项工作中,我们提出了一种名为 Context-Aware Network(CANet)的新型脑胶质瘤分割方法。CANet 从卷积空间和特征交互图中捕获具有上下文的高维且有区分力的特征。我们进一步提出了上下文引导的注意条件随机场,可以有选择地聚合特征。我们使用公开的脑胶质瘤分割数据集 BRATS2017、BRATS2018 和 BRATS2019 来评估我们的方法。实验结果表明,在训练集和验证集上,针对不同的分割指标,该算法在不同的分割指标下,其性能优于或与几种最先进的方法相当。