Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan, United States of America.
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan, United States of America.
PLoS One. 2021 Mar 16;16(3):e0248227. doi: 10.1371/journal.pone.0248227. eCollection 2021.
Cancer patients have been at the forefront of policy discussions leading to legalization of medical Cannabis (marijuana). Unfortunately, Cannabis use among those with cancer is poorly understood.
A diverse group of patients seeking certification for medical Cannabis in the state of Michigan were surveyed at the time of their presentation to medical dispensaries. The survey assessed demographics, employment/disability, pain, physical functioning, mental health, mode of Cannabis use, and frequency/amount of Cannabis use. Chi-square and t-tests were performed to compare those who did and did not endorse cancer diagnosis.
Analysis of data from 1485 adults pursuing medical Cannabis certification, including 72 (4.8%) reporting a cancer diagnosis, indicated that those with cancer were older [mean age 53.4 years (SD = 10.5) vs. 44.7 years (SD = 13.0); p<0.001] than those without cancer. They also differed regarding employment status (p<0.001; working: 20.8% vs. 46.2%; disabled: 44.4% vs. 26.5% for those with vs. those without cancer, respectively). Those with cancer used less Cannabis (p = 0.033 for quantity used) and used Cannabis less often (p = 0.032 for frequency of use); they less frequently endorsed smoking Cannabis (80% vs 91%; p = 0.015). There was a non-significant trend to increased edible use in those with cancer (57% vs. 44%; p = 0.052).
Patients with cancer who are seeking medical Cannabis are different from those seeking medical Cannabis without cancer, and they report using Cannabis differently. Further research to characterize the patterns and consequences of Cannabis use in cancer patients is needed.
癌症患者一直处于推动医用大麻（大麻）合法化政策讨论的前沿。不幸的是，癌症患者的大麻使用情况还没有得到很好的理解。
在密歇根州，寻求医用大麻认证的患者在向医疗药房就诊时接受了调查。该调查评估了人口统计学、就业/残疾、疼痛、身体功能、心理健康、大麻使用方式以及大麻使用频率/数量。使用卡方检验和 t 检验比较了那些支持和不支持癌症诊断的患者。
对 1485 名寻求医用大麻认证的成年人进行数据分析，其中 72 人（4.8%）报告患有癌症，结果表明，癌症患者年龄较大[平均年龄为 53.4 岁（标准差=10.5），而非癌症患者为 44.7 岁（标准差=13.0）；p<0.001]。他们在就业状况方面也存在差异（p<0.001；工作：20.8% vs. 46.2%；残疾：44.4% vs. 26.5%，分别为癌症患者和非癌症患者）。癌症患者使用的大麻较少（使用量：p = 0.033），使用频率较低（使用频率：p = 0.032），他们较少吸食大麻（80% vs. 91%；p = 0.015）。在癌症患者中，使用大麻食品的趋势增加（57% vs. 44%；p = 0.052）。
寻求医用大麻的癌症患者与那些不寻求医用大麻的癌症患者不同，他们报告的大麻使用方式也不同。需要进一步研究以描述癌症患者中大麻使用的模式和后果。
