Faculty of Dentistry, The University of Hong Kong, Prince Philip Dental Hospital, 34 Hospital Road, Sai Ying Pun, Hong Kong, China.
Faculty of Dentistry, The University of Hong Kong, Prince Philip Dental Hospital, 34 Hospital Road, Sai Ying Pun, Hong Kong, China.
J Dent. 2021 May;108:103638. doi: 10.1016/j.jdent.2021.103638. Epub 2021 Mar 13.
This systematic review aims to investigate the efficacy of denture adhesives (DAs) for complete dentures (CDs), and to provide clinical recommendations for prosthodontists and general practitioners.
DATA/SOURCES: Electronic databases (Medline, Embase, CENTRAL) and gray literatures were searched (up to March 2020) for relevant randomized and non-randomized controlled clinical trials (RCTs and CCTs) evaluating the efficacy of DAs when applied to CDs. Primary outcomes were objectively assessed variables directly related to mastication (denture retention, maximum bite force and masticatory efficiency). Secondary outcomes included other objectively assessed variables and patient-reported outcomes.
Of the 1729 records identified, 39 studies (43 articles) were included in the analysis. Among them, 23 were RCTs and 16 were CCTs, with two multicenter clinical trials (1 RCT and 1 CCT). Meta-analysis results indicated that DAs provided significantly higher retention (SMD 1.34, 95 % CI: 0.89-1.79, P < 0.001) for CDs. Bite force (SMD 0.98, 95 % CI: 0.50-1.47, P < 0.001) and masticatory performance (SMD 0.72, 95 % CI: 0.23-1.22, P = 0.004) of the CD wearers were also improved after using DAs, but the effect size was relatively smaller.
Based on the results of this systematic review, it is concluded that DAs can improve denture retention, bite force and masticatory performance of CD wearers.
This study investigated the effects of all types of DAs for CDs in terms of their effects on denture retention, masticatory performance, oral health-related quality of life and oral microorganisms for CD wearers.
本系统评价旨在研究义齿黏附剂（DAs）对全口义齿（CDs）的疗效，并为修复医生和全科医生提供临床建议。
电子数据库（Medline、Embase、CENTRAL）和灰色文献（截至 2020 年 3 月）中检索了评价 DAs 应用于 CDs 时疗效的随机和非随机对照临床试验（RCT 和 CCT）。主要结局是与咀嚼直接相关的客观评估变量（义齿固位、最大咬合力和咀嚼效率）。次要结局包括其他客观评估变量和患者报告结局。
在确定的 1729 条记录中，有 39 项研究（43 篇文章）纳入分析。其中，23 项为 RCT，16 项为 CCT，有两项多中心临床试验（1 项 RCT 和 1 项 CCT）。Meta 分析结果表明，DAs 显著提高了 CDs 的固位（SMD 1.34，95%CI：0.89-1.79，P<0.001）。使用 DAs 后，CD 佩戴者的咬合力（SMD 0.98，95%CI：0.50-1.47，P<0.001）和咀嚼性能（SMD 0.72，95%CI：0.23-1.22，P=0.004）也得到改善，但效果较小。
基于本系统评价的结果，得出结论认为 DAs 可以提高 CD 佩戴者的义齿固位、咬合力和咀嚼性能。
本研究调查了所有类型的 DAs 对 CD 佩戴者的义齿固位、咀嚼性能、口腔健康相关生活质量和口腔微生物的影响。
