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近视性视网膜脱离合并黄斑裂孔眼硅油取出术后的长期预后

Long-Term Outcome After Silicone Oil Removal in Eyes with Myopic Retinal Detachment Associated with Macular Hole.

作者信息

Ghoraba Hammouda Hamdy, Leila Mahmoud, Shebl Mohamed, Abdelhafez Mohamed Ahmed, Abdelfattah Haithem Maamoun

机构信息

Ophthalmology Department, Faculty of Medicine, Tanta University, Tanta, Egypt.

Magrabi Eye Hospital, Tanta, Egypt.

出版信息

Clin Ophthalmol. 2021 Mar 8;15:1003-1011. doi: 10.2147/OPTH.S298565. eCollection 2021.

Abstract

PURPOSE

To assess the efficacy of pars plana vitrectomy (PPV) and silicone oil tamponade for management of myopic retinal detachment associated with macular hole (MRDMH) and to assess the anatomical and functional outcomes of this technique and its long-term validity after silicone oil removal.

METHODS

Retrospective interventional non-comparative case series including consecutive patients who had PPV and silicone oil tamponade for MRDMH. All patients had an axial length ≥26 mm. Main outcome measures were retinal re-attachment and macular hole closure after silicone oil removal, improvement of best-corrected visual acuity (BCVA), and complications secondary to surgery. Chi square/Fisher's exact test was used to analyze categorical variables, while One-way ANOVA/Kruskal-Wallis test was used to compare variables across the closure type and complications. Correlations between numerical variables were tested using Spearman correlation. Kaplan-Meier method was used to estimate the event-free survival. P value is significant at 0.05.

RESULTS

The study included 26 eyes of 26 patients. Retinal re-attachment rate after primary and secondary surgeries was 88.4% and 100%, respectively. W-type macular hole closure occurred in 58% of eyes. Vision improved in 58% of eyes. Mean final BCVA was 0.05 decimal units, p = 0.004. Cataract and glaucoma developed in 42% and 15% of eyes, respectively. Initial BCVA, axial length and duration of silicone oil tamponade did not correlate significantly with either the type of macular hole closure or the final BCVA.

CONCLUSION

PPV and silicone oil tamponade technique promotes successful anatomical and functional outcome in MRDMH. Long-term success is maintained after silicone oil removal. High incidence of silicone oil-induced complications mandate its removal from eyes with successful retinal re-attachment.

摘要

目的

评估玻璃体切割术(PPV)联合硅油填充治疗伴有黄斑裂孔的高度近视性视网膜脱离(MRDMH)的疗效,并评估该技术的解剖和功能结局以及硅油取出后的长期有效性。

方法

回顾性介入性非对照病例系列研究,纳入连续接受PPV联合硅油填充治疗MRDMH的患者。所有患者眼轴长度≥26mm。主要观察指标为硅油取出后视网膜复位情况、黄斑裂孔闭合情况、最佳矫正视力(BCVA)改善情况以及手术相关并发症。采用卡方检验/费舍尔精确检验分析分类变量,采用单因素方差分析/克鲁斯卡尔-沃利斯检验比较不同闭合类型和并发症的变量。采用斯皮尔曼相关性检验数值变量之间的相关性。采用Kaplan-Meier法估计无事件生存率。P值<0.05具有统计学意义。

结果

该研究纳入26例患者的26只眼。初次手术和二次手术后视网膜复位率分别为88.4%和100%。58%的患眼出现W型黄斑裂孔闭合。58%的患眼视力改善。最终平均BCVA为0.05对数单位,p = 0.004。分别有42%和15%的患眼发生白内障和青光眼。初始BCVA、眼轴长度和硅油填充时间与黄斑裂孔闭合类型或最终BCVA均无显著相关性。

结论

PPV联合硅油填充技术可促进MRDMH获得成功的解剖和功能结局。硅油取出后可维持长期成功。硅油所致并发症发生率高,在视网膜复位成功后需取出硅油。

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