Horio T, Fujigaki K
Department of Dermatology, Faculty of Medicine, Kyoto University, Japan.
J Am Acad Dermatol. 1988 May;18(5 Pt 2):1189-93. doi: 10.1016/s0190-9622(88)70122-x.
A 24-year-old woman had solar urticaria that was activated by wavelengths ranging from 320 to 420 nm, mainly ultraviolet A light. The irradiation of visible light before exposure to activating wavelengths significantly enhanced an urticarial reaction in an augmentative but not in an additive fashion. The examinations using a monochromator revealed that the augmentation spectrum ranged from 450 to 500 nm. Postirradiation of the spectrum had no effect. The inhibition spectrum was also determined in longer wavelengths ranging from 550 to 600 nm. Both postirradiation and preirradiation of the inhibition spectrum exerted their effects. The augmentation spectrum revealed no effects on the wheal formation induced by histamine or compound 48/80 in the patient. The existence of augmentation spectrum has never been reported in solar urticaria, although the inhibition spectrum has been described by several authors.
一名24岁女性患有日光性荨麻疹,其由波长范围为320至420纳米的光线激活,主要是紫外线A光。在暴露于激活波长之前照射可见光会以增强而非相加的方式显著增强荨麻疹反应。使用单色仪进行的检查显示,增强光谱范围为450至500纳米。该光谱的照射后无影响。还在550至600纳米的较长波长范围内测定了抑制光谱。抑制光谱的照射后和照射前均发挥作用。增强光谱对该患者体内组胺或化合物48/80诱导的风团形成无影响。尽管已有多位作者描述了抑制光谱,但日光性荨麻疹中增强光谱的存在此前从未有过报道。