Steffen C
J Cutan Pathol. 1988 Apr;15(2):66-74. doi: 10.1111/j.1600-0560.1988.tb00522.x.
Twelve cases of actinic granuloma (O'Brien) are reported. It is concluded that actinic granuloma is a specific disease characterized by clinical lesions indistinguishable from granuloma annulare, but occurring on solar damaged skin. Histologically, elastic tissue is destroyed by the granulomatous process in actinic granuloma, but not in granuloma annulare. It would appear that actinic granuloma, granuloma multiforme, necrobiosis lipoidica of the face and scalp (Wilson-Jones) and Miescher's granuloma of the face (Mehregan and Altman) are the same disease.
报告了12例光化性肉芽肿（奥布赖恩型）。得出的结论是，光化性肉芽肿是一种特殊疾病，其临床损害与环状肉芽肿难以区分，但发生于日光损伤的皮肤。在组织学上，光化性肉芽肿的肉芽肿过程会破坏弹性组织，而环状肉芽肿则不会。看来光化性肉芽肿、多形性肉芽肿、面部和头皮类脂质渐进性坏死（威尔逊 - 琼斯型）以及面部米舍尔肉芽肿（梅雷根和阿尔特曼型）是同一种疾病。
