Jalalzadeh Mojgan, Chaudhari Ashok, Baumstein Donald
Internal Medicine/Nephrology, Metropolitan Hospital Center, New York Medical College, New York, USA.
Cureus. 2021 Feb 4;13(2):e13132. doi: 10.7759/cureus.13132.
Osmotic demyelination syndrome (ODS) is a demyelinating disorder of the central nervous system. It usually occurs with rapid correction of severe chronic hyponatremia. ODS is rarely seen as a complication of hyperglycemia. Herein, we report a rare presentation of ODS secondary to hyperosmolar hyperglycemic state. A 28-year-old female with type 1 diabetes, hypertension, seizure disorder, and end-stage renal disease on hemodialysis was brought from a shelter with two days of unresponsiveness and developed ODS after hyperosmolar hyperglycemic state in long-standing uncontrolled diabetes with normal serum electrolyte levels.
渗透性脱髓鞘综合征（ODS）是一种中枢神经系统的脱髓鞘疾病。它通常在严重慢性低钠血症快速纠正时发生。ODS很少作为高血糖症的并发症出现。在此，我们报告一例继发于高渗高血糖状态的ODS罕见病例。一名28岁的1型糖尿病女性患者，患有高血压、癫痫症且处于终末期肾病需血液透析，从收容所送来时已无反应两天，在长期未控制的糖尿病且血清电解质水平正常的情况下，出现高渗高血糖状态后发生了ODS。
