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基于深度卷积神经网络和全局特征的肺肿瘤计算机辅助诊断研究。

Computer-Aided Diagnosis Research of a Lung Tumor Based on a Deep Convolutional Neural Network and Global Features.

机构信息

School of Science, Ningxia Medical University, Yinchuan 750004, China.

Key Laboratory of Images & Graphics Intelligent Processing of State Ethnic Affairs Commission, North Minzu University, Yinchuan 750021, China.

出版信息

Biomed Res Int. 2021 Feb 28;2021:5513746. doi: 10.1155/2021/5513746. eCollection 2021.

Abstract

Based on the better generalization ability and the feature learning ability of the deep convolutional neural network, it is very significant to use the DCNN on the computer-aided diagnosis of a lung tumor. Firstly, a deep convolutional neural network was constructed according to the fuzzy characteristics and the complexity of lung CT images. Secondly, the relation between model parameters (iterations, different resolution) and recognition rate is discussed. Thirdly, the effects of different model structures for the identification of a lung tumor were analyzed by changing convolution kernel size, feature dimension, and depth of the network. Fourthly, the different optimization methods on how to influence the DCNN performance were discussed from three aspects containing pooling methods (maximum pooling and mean pooling), activation function (sigmoid and ReLU), and training algorithm (batch gradient descent and gradient descent with momentum). Finally, the experimental results verified the feasibility of DCNN used on computer-aided diagnosis of lung tumors, and it can achieve a good recognition rate when selecting the appropriate model parameters and model structure and using the method of gradient descent with momentum.

摘要

基于深度卷积神经网络更好的泛化能力和特征学习能力,将其应用于肺肿瘤的计算机辅助诊断具有重要意义。首先,根据肺 CT 图像的模糊特征和复杂性,构建了一个深度卷积神经网络。其次,讨论了模型参数(迭代次数、不同分辨率)与识别率之间的关系。第三,通过改变卷积核大小、网络特征维度和深度,分析了不同模型结构对肺肿瘤识别的影响。第四,从池化方法(最大池化和平均池化)、激活函数(sigmoid 和 ReLU)和训练算法(批量梯度下降和带动量的梯度下降)三个方面讨论了不同的优化方法对 DCNN 性能的影响。最后,实验结果验证了 DCNN 应用于肺肿瘤计算机辅助诊断的可行性,当选择合适的模型参数和模型结构并使用带动量的梯度下降法时,可以达到良好的识别率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afd4/7937457/d226da9bb1c8/BMRI2021-5513746.001.jpg

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