School of Computer Science and Engineering, North Minzu University, Yinchuan 750021, China.
School of Science, Ningxia Medical University, Yinchuan 750004, China.
Biomed Res Int. 2020 Dec 16;2020:6636321. doi: 10.1155/2020/6636321. eCollection 2020.
Nonnegative sparse representation has become a popular methodology in medical analysis and diagnosis in recent years. In order to resolve network degradation, higher dimensionality in feature extraction, data redundancy, and other issues faced when medical images parameters are trained using convolutional neural networks. Lung tumors in chest CT image based on nonnegative, sparse, and collaborative representation classification of DenseNet (DenseNet-NSCR) are proposed by this paper: firstly, initialization parameters of pretrained DenseNet model using transfer learning; secondly, training DenseNet using CT images to extract feature vectors for the full connectivity layer; thirdly, a nonnegative, sparse, and collaborative representation (NSCR) is used to represent the feature vector and solve the coding coefficient matrix; fourthly, the residual similarity is used for classification. The experimental results show that the DenseNet-NSCR classification is better than the other models, and the various evaluation indexes such as specificity and sensitivity are also high, and the method has better robustness and generalization ability through comparison experiment using AlexNet, GoogleNet, and DenseNet-201 models.
近年来,非负稀疏表示已成为医学分析和诊断领域的一种流行方法。为了解决网络退化、特征提取的高维度、数据冗余和其他问题,本文提出了基于非负、稀疏和协作表示分类的密集网络(DenseNet-NSCR)对胸部 CT 图像中的肺肿瘤进行分类:首先,使用迁移学习对预训练的 DenseNet 模型进行初始化参数;其次,使用 CT 图像对 DenseNet 进行训练,以提取全连接层的特征向量;然后,使用非负、稀疏和协作表示(NSCR)来表示特征向量并求解编码系数矩阵;最后,使用残差相似度进行分类。实验结果表明,DenseNet-NSCR 分类效果优于其他模型,特异性和敏感性等各项评价指标也较高,通过与 AlexNet、GoogleNet 和 DenseNet-201 模型的对比实验,该方法具有更好的鲁棒性和泛化能力。