Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Olympic-ro 33, Seoul, 05505, Republic of Korea.
Department of Clinical Epidemiology and Biostatistics, University of Ulsan College of Medicine, Asan Medical Center, Olympic-ro 33, Seoul, 05505, Republic of Korea.
Eur Radiol. 2021 Sep;31(9):6457-6470. doi: 10.1007/s00330-021-07760-w. Epub 2021 Mar 17.
To investigate the impact of acceleration factors on reproducibility of radiomic features in sensitivity encoding (SENSE) and compressed SENSE (CS), compare between SENSE and CS, and identify reproducible radiomic features.
Three-dimensional turbo spin echo T1-weighted imaging was performed in 14 healthy volunteers (mean age, 57 years; range, 33-67 years; 7 men) under SENSE and CS with accelerator factors of 5.5, 6.8, and 9.7. Eight anatomical locations (brain parenchyma, salivary glands, masseter muscle, tongue, pharyngeal mucosal space, eyeballs) were evaluated. Reproducibility of radiomic features was evaluated by calculating concordance correlation coefficient (CCC) in reference to the original image (SENSE with acceleration factor of 3.5). Reproducibility of radiomic features among acceleration factors and between SENSE and CS was compared.
Proportion of radiomic features with CCC > 0.85 in reference to the original image was lower with higher acceleration factors in both SENSE and CS across all anatomical locations (p < .001). Proportion of radiomic features with CCC > 0.85 in reference to the original image was higher in SENSE compared with CS (SENSE, 6.7-7.3% vs CS, 4.4-5.0%; p < .001). Run percentage of gray-level run-length matrix (GLRLM) with wavelet D showed CCC > 0.85 in reference to the original image in both SENSE and CS at acceleration factor of 9.7 in the highest number of anatomical locations.
Higher acceleration factors resulted in lower reproducibility of radiomic features in both SENSE and CS, and SENSE showed higher reproducibility of radiomic features than CS in reference to the original image. Run percentage of GLRLM with wavelet D was identified as the most reproducible feature.
• Reproducibility of radiomic features in reference to the original image was lower with higher acceleration factors in both sensitivity encoding (SENSE) and compressed SENSE (CS) across all anatomical locations (p < .001). • SENSE showed higher proportions of radiomic features with CCC > 0.85 in reference to the original image (SENSE, 6.7-7.3% vs CS, 4.4-5.0%; p < .001) compared with CS. • Run percentage of gray-level run-length matrix (GLRLM) with wavelet D showed CCC > 0.85 in reference to the original image in both SENSE and CS with the highest acceleration factor.
研究加速因子对敏感度编码（SENSE）和压缩敏感度编码（CS）中放射组学特征可重复性的影响，比较 SENSE 和 CS 之间的差异，并确定可重复的放射组学特征。
在 14 名健康志愿者（平均年龄 57 岁；范围 33-67 岁；7 名男性）中进行三维涡轮自旋回波 T1 加权成像，分别采用 SENSE 和 CS 加速因子为 5.5、6.8 和 9.7。评估 8 个解剖部位（脑实质、唾液腺、咬肌、舌、咽黏膜间隙、眼球）。通过计算与原始图像（SENSE 加速因子为 3.5）的一致性相关系数（CCC），评估放射组学特征的可重复性。比较不同加速因子和 SENSE 与 CS 之间放射组学特征的可重复性。
在 SENSE 和 CS 中，所有解剖部位的放射组学特征在较高加速因子时，与原始图像相比，CCC>0.85 的比例较低（p<0.001）。与 CS 相比，SENSE 中与原始图像相比，CCC>0.85 的放射组学特征比例更高（SENSE，6.7%-7.3%vs CS，4.4%-5.0%；p<0.001）。在 SENSE 和 CS 中，在加速因子为 9.7 时，使用小波 D 的灰度游程长度矩阵（GLRLM）的游程百分比显示出与原始图像的 CCC>0.85。
在 SENSE 和 CS 中，较高的加速因子导致放射组学特征的可重复性降低，与原始图像相比，SENSE 显示出更高的放射组学特征可重复性。使用小波 D 的灰度游程长度矩阵（GLRLM）的游程百分比被确定为最具可重复性的特征。
在所有解剖部位（p<0.001），SENSE 和 CS 中放射组学特征的可重复性随加速因子的增加而降低。
与 CS 相比，SENSE 中与原始图像相比，CCC>0.85 的放射组学特征比例更高（SENSE，6.7%-7.3%vs CS，4.4%-5.0%；p<0.001）。
在 SENSE 和 CS 中，在加速因子为 9.7 时，使用小波 D 的灰度游程长度矩阵（GLRLM）的游程百分比显示出与原始图像的 CCC>0.85。
