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五十只工作犬对侧髋关节骨关节炎的临床和影像学征象比较。

Comparison of clinical and radiographic signs of hip osteoarthritis in contralateral hip joints of fifty working dogs.

机构信息

Divisão de Medicina Veterinária, Guarda Nacional Republicana (GNR), Lisbon, Portugal.

MED-Mediterranean Institute for Agriculture, Environment and Development, Instituto de Investigação e Formação Avançada, Universidade de Évora, Évora, Portugal.

出版信息

PLoS One. 2021 Mar 18;16(3):e0248767. doi: 10.1371/journal.pone.0248767. eCollection 2021.

Abstract

OBJECTIVE

This study aimed to compare the symmetry of clinical and radiographic signs of right and left pelvic limbs of dogs with bilateral hip osteoarthritis (OA) and evaluate the association of physical findings and radiographic abnormalities.

PATIENTS AND METHODS

One hundred pelvic limbs of police working dogs with bilateral hip OA were evaluated, following a screening program. Weight distribution, joint range of motion at flexion and extension, thigh girth, and radiographic signs were recorded and compared with the results of the contralateral limb and by breed, age, and sex with the Paired Samples T-Test and Pearson correlation coefficient, with p<0.05.

RESULTS

The sample mean age was 6.5±2.2 years, and the bodyweight of 26.7±5.3kg. No significant differences were observed when comparing weight distribution, joint range of motion, and thigh girth of left and right limbs. Weight distribution and age showed a statistically significant correlation with joint extension. The right limbs showed a significantly higher frequency of circumferential femoral head osteophyte (CFHO) regarding radiographic signs. Limbs with CFHO or caudolateral curvilinear osteophyte had significantly larger joint flexion angle (p = 0.02) and smaller extension angle (p<0.01), respectively, compared to those that did not. Age showed a significant correlation with the presence of several radiographic findings, as did different breeds.

CONCLUSION

Clinical and radiographic signs occur symmetrically in naturally occurring hip OA in police working dogs. Several correlations were observed between the evaluations performed and differences between breeds, which can be useful in assessing and early diagnosis of hip OA.

摘要

目的

本研究旨在比较双侧髋关节骨关节炎(OA)犬的左右骨盆肢体的临床和影像学表现的对称性,并评估体格检查结果与影像学异常之间的相关性。

患者与方法

通过筛查计划,对 100 只患有双侧髋关节 OA 的警犬的骨盆肢体进行了评估。记录体重分布、屈伸关节活动度、大腿周长和影像学表现,并与对侧肢体以及按品种、年龄和性别进行比较,采用配对样本 T 检验和 Pearson 相关系数,p<0.05。

结果

样本的平均年龄为 6.5±2.2 岁,体重为 26.7±5.3kg。左右肢体的体重分布、关节活动度和大腿周长比较差异均无统计学意义。体重分布和年龄与关节伸展呈显著正相关。在影像学表现方面,右侧肢体的股骨头周缘骨赘(CFHO)发生率明显更高。与未出现 CFHO 或尾外侧曲线状骨赘的肢体相比,出现 CFHO 或尾外侧曲线状骨赘的肢体的关节屈曲角度明显更大(p = 0.02),而伸展角度明显更小(p<0.01)。年龄与存在多种影像学发现之间存在显著相关性,不同品种之间也存在相关性。

结论

在自然发生的警犬髋关节 OA 中,临床和影像学表现是对称的。评估结果与品种之间存在多种相关性,这对于髋关节 OA 的评估和早期诊断可能有用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae68/7971486/8ff757ce2b22/pone.0248767.g001.jpg

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